Reaction Details |
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Target | Trace amine-associated receptor 5 |
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Ligand | BDBM50053596 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1643991 (CHEMBL3992920) |
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EC50 | >10000±n/a nM |
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Citation | Tonelli, M; Espinoza, S; Gainetdinov, RR; Cichero, E Novel biguanide-based derivatives scouted as TAAR1 agonists: Synthesis, biological evaluation, ADME prediction and molecular docking studies. Eur J Med Chem127:781-792 (2017) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Trace amine-associated receptor 5 |
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Name: | Trace amine-associated receptor 5 |
Synonyms: | Gm227 | TAAR5_MOUSE | TaR-5 | Taar5 | Trace amine receptor 5 | Trace amine-associated receptor 5 | Trimethylamine receptor | mTaar5 |
Type: | PROTEIN |
Mol. Mass.: | 38230.08 |
Organism: | Mus musculus |
Description: | ChEMBL_116770 |
Residue: | 337 |
Sequence: | MRAVLLPGSGEQPTAFCYQVNGSCPRTVHPLAIQVVIYLACAVGVLITVLGNLFVVFAVS
YFKVLHTPTNFLLLSLALADMLLGLLVLPLSTVRSVESCWFFGDFLCRLHTYLDTLFCLT
SIFHLCFISIDRHCAICDPLLYPSKFTVRTALRYIVAGWGIPAAYTAFFLYTDVVERALS
QWLEEMPCVGSCQLLFNKFWGWLNFPAFFVPCLIMISLYLKIFVVATRQAQQIRTLSQSL
AGAVKRERKAAKTLGIAVGIYLVCWLPFTVDTLVDSLLNFITPPLVFDIFIWFAYFNSAC
NPIIYVFSYRWFRKALKLLLSREIFSPRTPTVDLYHD
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BDBM50053596 |
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n/a |
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Name | BDBM50053596 |
Synonyms: | 1-phenylbiguanide | CHEMBL13791 | N-phenylimidodicarbonimidic diamide | Phenyl biguanide |
Type | Small organic molecule |
Emp. Form. | C8H11N5 |
Mol. Mass. | 177.2064 |
SMILES | NC(=N)NC(N)=Nc1ccccc1 |w:6.6| |
Structure |
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