| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Trace amine-associated receptor 5 |
|---|
| Ligand | BDBM50227829 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1643991 (CHEMBL3992920) |
|---|
| EC50 | >10000±n/a nM |
|---|
| Citation |  Tonelli, M; Espinoza, S; Gainetdinov, RR; Cichero, E Novel biguanide-based derivatives scouted as TAAR1 agonists: Synthesis, biological evaluation, ADME prediction and molecular docking studies. Eur J Med Chem127:781-792 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Trace amine-associated receptor 5 |
|---|
| Name: | Trace amine-associated receptor 5 |
|---|
| Synonyms: | Gm227 | TAAR5_MOUSE | TaR-5 | Taar5 | Trace amine receptor 5 | Trace amine-associated receptor 5 | Trimethylamine receptor | mTaar5 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 38230.08 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_116770 |
|---|
| Residue: | 337 |
|---|
| Sequence: | MRAVLLPGSGEQPTAFCYQVNGSCPRTVHPLAIQVVIYLACAVGVLITVLGNLFVVFAVS
YFKVLHTPTNFLLLSLALADMLLGLLVLPLSTVRSVESCWFFGDFLCRLHTYLDTLFCLT
SIFHLCFISIDRHCAICDPLLYPSKFTVRTALRYIVAGWGIPAAYTAFFLYTDVVERALS
QWLEEMPCVGSCQLLFNKFWGWLNFPAFFVPCLIMISLYLKIFVVATRQAQQIRTLSQSL
AGAVKRERKAAKTLGIAVGIYLVCWLPFTVDTLVDSLLNFITPPLVFDIFIWFAYFNSAC
NPIIYVFSYRWFRKALKLLLSREIFSPRTPTVDLYHD
|
|
|
|---|
| BDBM50227829 |
|---|
| n/a |
|---|
| Name | BDBM50227829 |
|---|
| Synonyms: | CHEBI:8455 | CHLOROGUANIDE | Proguanil |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H16ClN5 |
|---|
| Mol. Mass. | 253.731 |
|---|
| SMILES | CC(C)NC(=N)NC(=N)Nc1ccc(Cl)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
