| Reaction Details |
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 | Report a problem with these data |
| Target | Lysophosphatidic acid receptor 2 |
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| Ligand | BDBM50233165 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1649786 (CHEMBL3998920) |
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| EC50 | 3±n/a nM |
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| Citation |  Banerjee, S; Norman, DD; Lee, SC; Parrill, AL; Pham, TC; Baker, DL; Tigyi, GJ; Miller, DD Highly Potent Non-Carboxylic Acid Autotaxin Inhibitors Reduce Melanoma Metastasis and Chemotherapeutic Resistance of Breast Cancer Stem Cells. J Med Chem60:1309-1324 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lysophosphatidic acid receptor 2 |
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| Name: | Lysophosphatidic acid receptor 2 |
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| Synonyms: | EDG4 | LPA receptor 2 | LPA-2 | LPA2 | LPAR2 | LPAR2_HUMAN | Lysophosphatidic acid receptor 2 | Lysophosphatidic acid receptor Edg-4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39103.44 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1451385 |
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| Residue: | 351 |
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| Sequence: | MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASN
RRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVA
TLLAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSR
MAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLV
KTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDA
EMRRTFRRLLCCACLRQSTRESVHYTSSAQGGASTRIMLPENGHPLMDSTL
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| BDBM50233165 |
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| n/a |
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| Name | BDBM50233165 |
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| Synonyms: | CHEMBL1222042 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H41O7P |
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| Mol. Mass. | 436.5198 |
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| SMILES | CCCCCCCC\C=C/CCCCCCCC(=O)OCC(O)COP(O)(O)=O |
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| Structure | 
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