Compile Data Set for Download or QSAR

Found 104 hits with Last Name = 'pham' and Initial = 'tc'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50316078 ((5-amino-3-((4'-((8-amino-1-hydroxy-3,6-disulfo-2-...) Show SMILES COc1cc(ccc1N=Nc1c(O)c2c(N)cc(cc2cc1S(O)(=O)=O)S(O)(=O)=O)-c1ccc(N=Nc2c(O)c3c(N)cc(cc3cc2S(O)(=O)=O)S(O)(=O)=O)c(OC)c1 |w:8.8,34.36| Show InChI InChI=1S/C34H28N6O16S4/c1-55-25-9-15(3-5-23(25)37-39-31-27(59(49,50)51)11-17-7-19(57(43,44)45)13-21(35)29(17)33(31)41)16-4-6-24(26(10-16)56-2)38-40-32-28(60(52,53)54)12-18-8-20(58(46,47)48)14-22(36)30(18)34(32)42/h3-14,41-42H,35-36H2,1-2H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	271	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant C-terminal FLAG-tagged autotaxin expressed in baculovirus-infected Sf9 cells assessed as FS-3 hydrolysis ...				J Med Chem 53: 3095-105 (2010) Article DOI: 10.1021/jm901718z BindingDB Entry DOI: 10.7270/Q2QZ2BXS
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50332461 ((R)-3-carba cyclic-phosphatidic acid | CHEMBL16300...) Show SMILES CCCCCCCCCCCCCCCCCC(=O)OC[C@H]1CCP([O-])(=O)O1 |r| Show InChI InChI=1S/C22H43O5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(23)26-20-21-18-19-28(24,25)27-21/h21H,2-20H2,1H3,(H,24,25)/p-1/t21-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant ATX mediated hydrolysis of FS-3				Bioorg Med Chem Lett 20: 7525-8 (2010) Article DOI: 10.1016/j.bmcl.2010.09.115 BindingDB Entry DOI: 10.7270/Q2XD11X1
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50366944 (Azovan Blue | Azovan sodium | EVANS BLUE) Show SMILES Cc1cc(ccc1N=Nc1ccc2c(cc(c(N)c2c1O)S([O-])(=O)=O)S([O-])(=O)=O)-c1ccc(N=Nc2ccc3c(cc(c(N)c3c2O)S([O-])(=O)=O)S([O-])(=O)=O)c(C)c1 |w:34.37,7.7| Show InChI InChI=1S/C34H28N6O14S4/c1-15-11-17(3-7-21(15)37-39-23-9-5-19-25(55(43,44)45)13-27(57(49,50)51)31(35)29(19)33(23)41)18-4-8-22(16(2)12-18)38-40-24-10-6-20-26(56(46,47)48)14-28(58(52,53)54)32(36)30(20)34(24)42/h3-14,41-42H,35-36H2,1-2H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54)/p-4	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	824	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant C-terminal FLAG-tagged autotaxin expressed in baculovirus-infected Sf9 cells assessed as FS-3 hydrolysis ...				J Med Chem 53: 3095-105 (2010) Article DOI: 10.1021/jm901718z BindingDB Entry DOI: 10.7270/Q2QZ2BXS
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50316087 (7-[(4-{[4-({4-[(6,8-disulfonaphthalen-2-yl)carbamo...) Show SMILES OC1=C(Nc2ccc(cc2)C(=O)Nc2ccc3cc(cc(c3c2)S(O)(=O)=O)S(O)(=O)=O)C(=O)C(O)=C(Nc2ccc(cc2)C(=O)Nc2ccc3cc(cc(c3c2)S(O)(=O)=O)S(O)(=O)=O)C1=O |c:1,t:37| Show InChI InChI=1S/C40H28N4O18S4/c45-35-33(41-23-7-1-19(2-8-23)39(49)43-25-11-5-21-13-27(63(51,52)53)17-31(29(21)15-25)65(57,58)59)36(46)38(48)34(37(35)47)42-24-9-3-20(4-10-24)40(50)44-26-12-6-22-14-28(64(54,55)56)18-32(30(22)16-26)66(60,61)62/h1-18,41-42,45,48H,(H,43,49)(H,44,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant C-terminal FLAG-tagged autotaxin expressed in baculovirus-infected Sf9 cells assessed as FS-3 hydrolysis ...				J Med Chem 53: 3095-105 (2010) Article DOI: 10.1021/jm901718z BindingDB Entry DOI: 10.7270/Q2QZ2BXS
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50316081 (5-amino-2-((4'-((6-amino-3-hydroxy-1-sulfonaphthal...) Show SMILES Nc1ccc2c(c(N=Nc3ccc(cc3)-c3ccc(cc3)N=Nc3c(O)c4c(N)cc(cc4cc3S(O)(=O)=O)S(O)(=O)=O)c(O)cc2c1)S(O)(=O)=O |w:21.22,8.8| Show InChI InChI=1S/C32H24N6O11S3/c33-20-5-10-24-18(11-20)13-26(39)29(32(24)52(47,48)49)37-35-21-6-1-16(2-7-21)17-3-8-22(9-4-17)36-38-30-27(51(44,45)46)14-19-12-23(50(41,42)43)15-25(34)28(19)31(30)40/h1-15,39-40H,33-34H2,(H,41,42,43)(H,44,45,46)(H,47,48,49)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.46E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant C-terminal FLAG-tagged autotaxin expressed in baculovirus-infected Sf9 cells assessed as FS-3 hydrolysis ...				J Med Chem 53: 3095-105 (2010) Article DOI: 10.1021/jm901718z BindingDB Entry DOI: 10.7270/Q2QZ2BXS
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50332460 ((S)-carba cyclic-phosphatidic acid | CHEMBL1630084) Show SMILES CCCCCCCCCCCCCCCCCC(=O)OC[C@@H]1CCP([O-])(=O)O1 |r| Show InChI InChI=1S/C22H43O5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(23)26-20-21-18-19-28(24,25)27-21/h21H,2-20H2,1H3,(H,24,25)/p-1/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant ATX mediated hydrolysis of FS-3				Bioorg Med Chem Lett 20: 7525-8 (2010) Article DOI: 10.1016/j.bmcl.2010.09.115 BindingDB Entry DOI: 10.7270/Q2XD11X1
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50079267 (Congo Red | Direct red 28 | Kongorot | Sodium diph...) Show SMILES Nc1c(cc(c2ccccc12)S([O-])(=O)=O)\N=N\c1ccc(cc1)-c1ccc(cc1)\N=N\c1cc(c2ccccc2c1N)S([O-])(=O)=O Show InChI InChI=1S/C32H24N6O6S2/c33-31-25-7-3-1-5-23(25)29(45(39,40)41)17-27(31)37-35-21-13-9-19(10-14-21)20-11-15-22(16-12-20)36-38-28-18-30(46(42,43)44)24-6-2-4-8-26(24)32(28)34/h1-18H,33-34H2,(H,39,40,41)(H,42,43,44)/p-2/b37-35+,38-36+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	1.89E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Noncompetitive inhibition of human recombinant C-terminal FLAG-tagged autotaxin expressed in baculovirus-infected Sf9 cells assessed as FS-3 hydrolys...				J Med Chem 53: 3095-105 (2010) Article DOI: 10.1021/jm901718z BindingDB Entry DOI: 10.7270/Q2QZ2BXS
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50300214 (2-(4-((3,5-dichlorophenyl)carbamothioyl)piperazin-...) Show SMILES CCn1cc(C(O)=O)c(=O)c2cnc(nc12)N1CCN(CC1)C(=S)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C21H20Cl2N6O3S/c1-2-27-11-16(19(31)32)17(30)15-10-24-20(26-18(15)27)28-3-5-29(6-4-28)21(33)25-14-8-12(22)7-13(23)9-14/h7-11H,2-6H2,1H3,(H,25,33)(H,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Competitive-type inhibition of autotaxin-mediated FS3 hydrolysis by Michaelis-Menton analysis				Bioorg Med Chem 18: 769-76 (2010) Article DOI: 10.1016/j.bmc.2009.11.056 BindingDB Entry DOI: 10.7270/Q2RR1ZBG
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50308960 (2-(4-((9H-xanthene-9-carbonyl)carbamothioyl)pipera...) Show SMILES CCn1cc(C(O)=O)c(=O)c2cnc(nc12)N1CCN(CC1)C(=S)NC(=O)C1c2ccccc2Oc2ccccc12 Show InChI InChI=1S/C29H26N6O5S/c1-2-33-16-20(27(38)39)24(36)19-15-30-28(31-25(19)33)34-11-13-35(14-12-34)29(41)32-26(37)23-17-7-3-5-9-21(17)40-22-10-6-4-8-18(22)23/h3-10,15-16,23H,2,11-14H2,1H3,(H,38,39)(H,32,37,41)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Competitive-type inhibition of autotaxin-mediated pNP-TMP hydrolysis by Michaelis-Menton analysis				Bioorg Med Chem 18: 769-76 (2010) Article DOI: 10.1016/j.bmc.2009.11.056 BindingDB Entry DOI: 10.7270/Q2RR1ZBG
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50308960 (2-(4-((9H-xanthene-9-carbonyl)carbamothioyl)pipera...) Show SMILES CCn1cc(C(O)=O)c(=O)c2cnc(nc12)N1CCN(CC1)C(=S)NC(=O)C1c2ccccc2Oc2ccccc12 Show InChI InChI=1S/C29H26N6O5S/c1-2-33-16-20(27(38)39)24(36)19-15-30-28(31-25(19)33)34-11-13-35(14-12-34)29(41)32-26(37)23-17-7-3-5-9-21(17)40-22-10-6-4-8-18(22)23/h3-10,15-16,23H,2,11-14H2,1H3,(H,38,39)(H,32,37,41)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Mixed-type inhibition of autotaxin-mediated FS3 hydrolysis by Michaelis-Menton analysis				Bioorg Med Chem 18: 769-76 (2010) Article DOI: 10.1016/j.bmc.2009.11.056 BindingDB Entry DOI: 10.7270/Q2RR1ZBG
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50308959 (4,4'-(5,5'-carbonylbis(1,3-dioxoisoindoline-5,2-di...) Show SMILES OC(=O)c1ccc(CN2C(=O)c3ccc(cc3C2=O)C(=O)c2ccc3C(=O)N(Cc4ccc(cc4)C(O)=O)C(=O)c3c2)cc1 Show InChI InChI=1S/C33H20N2O9/c36-27(21-9-11-23-25(13-21)30(39)34(28(23)37)15-17-1-5-19(6-2-17)32(41)42)22-10-12-24-26(14-22)31(40)35(29(24)38)16-18-3-7-20(8-4-18)33(43)44/h1-14H,15-16H2,(H,41,42)(H,43,44)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Competitive-type inhibition of autotaxin-mediated FS3 hydrolysis by Michaelis-Menton analysis				Bioorg Med Chem 18: 769-76 (2010) Article DOI: 10.1016/j.bmc.2009.11.056 BindingDB Entry DOI: 10.7270/Q2RR1ZBG
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50308958 (4-(4-(2-(naphthalen-1-yl)-1,3-dioxoisoindoline-5-c...) Show SMILES OC(=O)c1ccc(Oc2ccc(cc2)C(=O)c2ccc3C(=O)N(C(=O)c3c2)c2cccc3ccccc23)cc1 Show InChI InChI=1S/C32H19NO6/c34-29(20-8-13-23(14-9-20)39-24-15-10-21(11-16-24)32(37)38)22-12-17-26-27(18-22)31(36)33(30(26)35)28-7-3-5-19-4-1-2-6-25(19)28/h1-18H,(H,37,38)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Mixed-type inhibition of autotaxin-mediated FS3 hydrolysis by Michaelis-Menton analysis				Bioorg Med Chem 18: 769-76 (2010) Article DOI: 10.1016/j.bmc.2009.11.056 BindingDB Entry DOI: 10.7270/Q2RR1ZBG
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50308961 (4-(2-(3-ethyl-4-oxo-3,4,6,7,8,9-hexahydropyrimido[...) Show SMILES CCn1c(SCC(=O)Nc2ccc(cc2)C(O)=O)nc2nc3CCCCc3cc2c1=O Show InChI InChI=1S/C22H22N4O4S/c1-2-26-20(28)16-11-14-5-3-4-6-17(14)24-19(16)25-22(26)31-12-18(27)23-15-9-7-13(8-10-15)21(29)30/h7-11H,2-6,12H2,1H3,(H,23,27)(H,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Noncompetitive inhibition of autotaxin-mediated FS3 hydrolysis by Michaelis-Menton analysis				Bioorg Med Chem 18: 769-76 (2010) Article DOI: 10.1016/j.bmc.2009.11.056 BindingDB Entry DOI: 10.7270/Q2RR1ZBG
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50300214 (2-(4-((3,5-dichlorophenyl)carbamothioyl)piperazin-...) Show SMILES CCn1cc(C(O)=O)c(=O)c2cnc(nc12)N1CCN(CC1)C(=S)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C21H20Cl2N6O3S/c1-2-27-11-16(19(31)32)17(30)15-10-24-20(26-18(15)27)28-3-5-29(6-4-28)21(33)25-14-8-12(22)7-13(23)9-14/h7-11H,2-6H2,1H3,(H,25,33)(H,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Noncompetitive inhibition of autotaxin-mediated pNP-TMP hydrolysis by Michaelis-Menton analysis				Bioorg Med Chem 18: 769-76 (2010) Article DOI: 10.1016/j.bmc.2009.11.056 BindingDB Entry DOI: 10.7270/Q2RR1ZBG
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50300214 (2-(4-((3,5-dichlorophenyl)carbamothioyl)piperazin-...) Show SMILES CCn1cc(C(O)=O)c(=O)c2cnc(nc12)N1CCN(CC1)C(=S)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C21H20Cl2N6O3S/c1-2-27-11-16(19(31)32)17(30)15-10-24-20(26-18(15)27)28-3-5-29(6-4-28)21(33)25-14-8-12(22)7-13(23)9-14/h7-11H,2-6H2,1H3,(H,25,33)(H,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Noncompetitive inhibition of autotaxin-mediated pNP-TMP hydrolysis by Michaelis-Menton analysis for enzyme-substrate complex				Bioorg Med Chem 18: 769-76 (2010) Article DOI: 10.1016/j.bmc.2009.11.056 BindingDB Entry DOI: 10.7270/Q2RR1ZBG
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50308961 (4-(2-(3-ethyl-4-oxo-3,4,6,7,8,9-hexahydropyrimido[...) Show SMILES CCn1c(SCC(=O)Nc2ccc(cc2)C(O)=O)nc2nc3CCCCc3cc2c1=O Show InChI InChI=1S/C22H22N4O4S/c1-2-26-20(28)16-11-14-5-3-4-6-17(14)24-19(16)25-22(26)31-12-18(27)23-15-9-7-13(8-10-15)21(29)30/h7-11H,2-6,12H2,1H3,(H,23,27)(H,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Noncompetitive inhibition of autotaxin-mediated FS3 hydrolysis by Michaelis-Menton analysis for enzyme-substrate complex				Bioorg Med Chem 18: 769-76 (2010) Article DOI: 10.1016/j.bmc.2009.11.056 BindingDB Entry DOI: 10.7270/Q2RR1ZBG
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50308957 (3-(1,3-dioxo-2-(4-(phenyldiazenyl)phenyl)isoindoli...) Show SMILES OC(=O)c1cccc(NC(=O)c2ccc3C(=O)N(C(=O)c3c2)c2ccc(cc2)\N=N\c2ccccc2)c1 Show InChI InChI=1S/C28H18N4O5/c33-25(29-21-8-4-5-18(15-21)28(36)37)17-9-14-23-24(16-17)27(35)32(26(23)34)22-12-10-20(11-13-22)31-30-19-6-2-1-3-7-19/h1-16H,(H,29,33)(H,36,37)/b31-30+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.51E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Mixed-type inhibition of autotaxin-mediated FS3 hydrolysis by Michaelis-Menton analysis				Bioorg Med Chem 18: 769-76 (2010) Article DOI: 10.1016/j.bmc.2009.11.056 BindingDB Entry DOI: 10.7270/Q2RR1ZBG
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50308960 (2-(4-((9H-xanthene-9-carbonyl)carbamothioyl)pipera...) Show SMILES CCn1cc(C(O)=O)c(=O)c2cnc(nc12)N1CCN(CC1)C(=S)NC(=O)C1c2ccccc2Oc2ccccc12 Show InChI InChI=1S/C29H26N6O5S/c1-2-33-16-20(27(38)39)24(36)19-15-30-28(31-25(19)33)34-11-13-35(14-12-34)29(41)32-26(37)23-17-7-3-5-9-21(17)40-22-10-6-4-8-18(22)23/h3-10,15-16,23H,2,11-14H2,1H3,(H,38,39)(H,32,37,41)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	1.98E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Mixed-type inhibition of autotaxin-mediated FS3 hydrolysis by Michaelis-Menton analysis for enzyme-substrate complex				Bioorg Med Chem 18: 769-76 (2010) Article DOI: 10.1016/j.bmc.2009.11.056 BindingDB Entry DOI: 10.7270/Q2RR1ZBG
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50308958 (4-(4-(2-(naphthalen-1-yl)-1,3-dioxoisoindoline-5-c...) Show SMILES OC(=O)c1ccc(Oc2ccc(cc2)C(=O)c2ccc3C(=O)N(C(=O)c3c2)c2cccc3ccccc23)cc1 Show InChI InChI=1S/C32H19NO6/c34-29(20-8-13-23(14-9-20)39-24-15-10-21(11-16-24)32(37)38)22-12-17-26-27(18-22)31(36)33(30(26)35)28-7-3-5-19-4-1-2-6-25(19)28/h1-18H,(H,37,38)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	3.23E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Mixed-type inhibition of autotaxin-mediated FS3 hydrolysis by Michaelis-Menton analysis for enzyme-substrate complex				Bioorg Med Chem 18: 769-76 (2010) Article DOI: 10.1016/j.bmc.2009.11.056 BindingDB Entry DOI: 10.7270/Q2RR1ZBG
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50308957 (3-(1,3-dioxo-2-(4-(phenyldiazenyl)phenyl)isoindoli...) Show SMILES OC(=O)c1cccc(NC(=O)c2ccc3C(=O)N(C(=O)c3c2)c2ccc(cc2)\N=N\c2ccccc2)c1 Show InChI InChI=1S/C28H18N4O5/c33-25(29-21-8-4-5-18(15-21)28(36)37)17-9-14-23-24(16-17)27(35)32(26(23)34)22-12-10-20(11-13-22)31-30-19-6-2-1-3-7-19/h1-16H,(H,29,33)(H,36,37)/b31-30+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.03E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Mixed-type inhibition of autotaxin-mediated FS3 hydrolysis by Michaelis-Menton analysis for enzyme-substrate complex				Bioorg Med Chem 18: 769-76 (2010) Article DOI: 10.1016/j.bmc.2009.11.056 BindingDB Entry DOI: 10.7270/Q2RR1ZBG
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233168 (CHEMBL4085965 | US11124490, Compound 11) Show SMILES Fc1cc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc(F)c1F Show InChI InChI=1S/C17H13Cl2F3N2O4S/c18-11-8-12(19)15(29(26,27)24-1-3-28-4-2-24)7-10(11)17(25)23-9-5-13(20)16(22)14(21)6-9/h5-8H,1-4H2,(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233187 (CHEMBL4079588) Show SMILES Fc1cc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)c(Br)c(F)c1F Show InChI InChI=1S/C17H12BrCl2F3N2O4S/c18-14-12(7-11(21)15(22)16(14)23)24-17(26)8-5-13(10(20)6-9(8)19)30(27,28)25-1-3-29-4-2-25/h5-7H,1-4H2,(H,24,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233154 (CHEMBL4096134 | US11124490, Compound 10) Show SMILES Fc1ccc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc1F Show InChI InChI=1S/C17H14Cl2F2N2O4S/c18-12-9-13(19)16(28(25,26)23-3-5-27-6-4-23)8-11(12)17(24)22-10-1-2-14(20)15(21)7-10/h1-2,7-9H,3-6H2,(H,22,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233173 (CHEMBL4094366 | US11124490, Compound 14) Show SMILES Fc1cc(NC(=S)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc(F)c1F Show InChI InChI=1S/C17H13Cl2F3N2O3S2/c18-11-8-12(19)15(29(25,26)24-1-3-27-4-2-24)7-10(11)17(28)23-9-5-13(20)16(22)14(21)6-9/h5-8H,1-4H2,(H,23,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233166 (CHEMBL4060128 | US11124490, Compound 3g) Show SMILES Fc1c(Cl)cc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc1Cl Show InChI InChI=1S/C17H13Cl4FN2O4S/c18-11-8-12(19)15(29(26,27)24-1-3-28-4-2-24)7-10(11)17(25)23-9-5-13(20)16(22)14(21)6-9/h5-8H,1-4H2,(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233155 (CHEMBL4080953 | US11124490, Compound 28b) Show SMILES CN1CCN(CC1)S(=O)(=O)c1cc(C(=O)Nc2cc(Cl)c(F)c(Cl)c2)c(Cl)cc1Cl Show InChI InChI=1S/C18H16Cl4FN3O3S/c1-25-2-4-26(5-3-25)30(28,29)16-8-11(12(19)9-13(16)20)18(27)24-10-6-14(21)17(23)15(22)7-10/h6-9H,2-5H2,1H3,(H,24,27)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of ATX (unknown origin) expressed in human A2058 cells assessed as inhibition of LPC-induced cell invasion after 20 hrs by calcein-AM dye ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233157 (CHEMBL4097500 | US11124490, Compound 28a) Show SMILES CN1CCN(CC1)S(=O)(=O)c1cc(C(=O)Nc2cc(F)c(F)c(F)c2)c(Cl)cc1Cl Show InChI InChI=1S/C18H16Cl2F3N3O3S/c1-25-2-4-26(5-3-25)30(28,29)16-8-11(12(19)9-13(16)20)18(27)24-10-6-14(21)17(23)15(22)7-10/h6-9H,2-5H2,1H3,(H,24,27)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233170 (CHEMBL4073772 | US11124490, Compound 13) Show SMILES Fc1ccc(NC(=S)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc1F Show InChI InChI=1S/C17H14Cl2F2N2O3S2/c18-12-9-13(19)16(28(24,25)23-3-5-26-6-4-23)8-11(12)17(27)22-10-1-2-14(20)15(21)7-10/h1-2,7-9H,3-6H2,(H,22,27)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233169 (CHEMBL4082022 | US11124490, Compound 3f) Show SMILES Fc1cc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc(F)c1Cl Show InChI InChI=1S/C17H13Cl3F2N2O4S/c18-11-8-12(19)15(29(26,27)24-1-3-28-4-2-24)7-10(11)17(25)23-9-5-13(21)16(20)14(22)6-9/h5-8H,1-4H2,(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233171 (CHEMBL4099620 | US11124490, Compound 15) Show SMILES Fc1c(Cl)cc(NC(=S)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc1Cl Show InChI InChI=1S/C17H13Cl4FN2O3S2/c18-11-8-12(19)15(29(25,26)24-1-3-27-4-2-24)7-10(11)17(28)23-9-5-13(20)16(22)14(21)6-9/h5-8H,1-4H2,(H,23,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233164 (CHEMBL4105201 | US11124490, Compound 29) Show SMILES CN1CCN(CC1)S(=O)(=O)c1cc(C(=S)Nc2cc(Cl)c(F)c(Cl)c2)c(Cl)cc1Cl Show InChI InChI=1S/C18H16Cl4FN3O2S2/c1-25-2-4-26(5-3-25)30(27,28)16-8-11(12(19)9-13(16)20)18(29)24-10-6-14(21)17(23)15(22)7-10/h6-9H,2-5H2,1H3,(H,24,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50187686 (CHEMBL3828074 | US10526329, Compound 2 | US1107261...) Show SMILES CCc1nc2c(C)cc(cn2c1N(C)c1nc(c(s1)C#N)-c1ccc(F)cc1)N1CCN(CC(=O)N2CC(O)C2)CC1 Show InChI InChI=1S/C30H33FN8O2S/c1-4-24-29(35(3)30-34-27(25(14-32)42-30)20-5-7-21(31)8-6-20)39-15-22(13-19(2)28(39)33-24)37-11-9-36(10-12-37)18-26(41)38-16-23(40)17-38/h5-8,13,15,23,40H,4,9-12,16-18H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of ATX (unknown origin)				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50187687 (CHEMBL3828733 | US11124490, Compound 918013) Show SMILES Fc1cccc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)c1 Show InChI InChI=1S/C17H15Cl2FN2O4S/c18-14-10-15(19)16(27(24,25)22-4-6-26-7-5-22)9-13(14)17(23)21-12-3-1-2-11(20)8-12/h1-3,8-10H,4-7H2,(H,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	116	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of ATX (unknown origin)				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50187687 (CHEMBL3828733 | US11124490, Compound 918013) Show SMILES Fc1cccc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)c1 Show InChI InChI=1S/C17H15Cl2FN2O4S/c18-14-10-15(19)16(27(24,25)22-4-6-26-7-5-22)9-13(14)17(23)21-12-3-1-2-11(20)8-12/h1-3,8-10H,4-7H2,(H,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	117	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233163 (CHEMBL4102111 | US11124490, Compound 12) Show SMILES Fc1cccc(NC(=S)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)c1 Show InChI InChI=1S/C17H15Cl2FN2O3S2/c18-14-10-15(19)16(27(23,24)22-4-6-25-7-5-22)9-13(14)17(26)21-12-3-1-2-11(20)8-12/h1-3,8-10H,4-7H2,(H,21,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	121	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233160 (CHEMBL4071490 | US11124490, Compound 3h) Show SMILES Fc1cc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc(F)c1C#N Show InChI InChI=1S/C18H13Cl2F2N3O4S/c19-13-8-14(20)17(30(27,28)25-1-3-29-4-2-25)7-11(13)18(26)24-10-5-15(21)12(9-23)16(22)6-10/h5-8H,1-4H2,(H,24,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50316078 ((5-amino-3-((4'-((8-amino-1-hydroxy-3,6-disulfo-2-...) Show SMILES COc1cc(ccc1N=Nc1c(O)c2c(N)cc(cc2cc1S(O)(=O)=O)S(O)(=O)=O)-c1ccc(N=Nc2c(O)c3c(N)cc(cc3cc2S(O)(=O)=O)S(O)(=O)=O)c(OC)c1 |w:8.8,34.36| Show InChI InChI=1S/C34H28N6O16S4/c1-55-25-9-15(3-5-23(25)37-39-31-27(59(49,50)51)11-17-7-19(57(43,44)45)13-21(35)29(17)33(31)41)16-4-6-24(26(10-16)56-2)38-40-32-28(60(52,53)54)12-18-8-20(58(46,47)48)14-22(36)30(18)34(32)42/h3-14,41-42H,35-36H2,1-2H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	372	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Inhibition of human recombinant C-terminal FLAG-tagged autotaxin expressed in baculovirus-infected Sf9 cells assessed as FS-3 hydrolysis				J Med Chem 53: 3095-105 (2010) Article DOI: 10.1021/jm901718z BindingDB Entry DOI: 10.7270/Q2QZ2BXS
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233161 (CHEMBL4084129) Show SMILES Fc1cc(NCc2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc(F)c1F Show InChI InChI=1S/C17H15Cl2F3N2O3S/c18-12-8-13(19)16(28(25,26)24-1-3-27-4-2-24)5-10(12)9-23-11-6-14(20)17(22)15(21)7-11/h5-8,23H,1-4,9H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	396	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233173 (CHEMBL4094366 | US11124490, Compound 14) Show SMILES Fc1cc(NC(=S)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc(F)c1F Show InChI InChI=1S/C17H13Cl2F3N2O3S2/c18-11-8-12(19)15(29(25,26)24-1-3-27-4-2-24)7-10(11)17(28)23-9-5-13(20)16(22)14(21)6-9/h5-8H,1-4H2,(H,23,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	403	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of ATX (unknown origin) expressed in human A2058 cells assessed as inhibition of LPC-induced cell invasion after 20 hrs by calcein-AM dye ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233154 (CHEMBL4096134 | US11124490, Compound 10) Show SMILES Fc1ccc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc1F Show InChI InChI=1S/C17H14Cl2F2N2O4S/c18-12-9-13(19)16(28(25,26)23-3-5-27-6-4-23)8-11(12)17(24)22-10-1-2-14(20)15(21)7-10/h1-2,7-9H,3-6H2,(H,22,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	528	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of ATX (unknown origin) expressed in human A2058 cells assessed as inhibition of LPC-induced cell invasion after 20 hrs by calcein-AM dye ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233169 (CHEMBL4082022 | US11124490, Compound 3f) Show SMILES Fc1cc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc(F)c1Cl Show InChI InChI=1S/C17H13Cl3F2N2O4S/c18-11-8-12(19)15(29(26,27)24-1-3-28-4-2-24)7-10(11)17(25)23-9-5-13(21)16(20)14(22)6-9/h5-8H,1-4H2,(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of ATX (unknown origin) expressed in human A2058 cells assessed as inhibition of LPC-induced cell invasion after 20 hrs by calcein-AM dye ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50316087 (7-[(4-{[4-({4-[(6,8-disulfonaphthalen-2-yl)carbamo...) Show SMILES OC1=C(Nc2ccc(cc2)C(=O)Nc2ccc3cc(cc(c3c2)S(O)(=O)=O)S(O)(=O)=O)C(=O)C(O)=C(Nc2ccc(cc2)C(=O)Nc2ccc3cc(cc(c3c2)S(O)(=O)=O)S(O)(=O)=O)C1=O |c:1,t:37| Show InChI InChI=1S/C40H28N4O18S4/c45-35-33(41-23-7-1-19(2-8-23)39(49)43-25-11-5-21-13-27(63(51,52)53)17-31(29(21)15-25)65(57,58)59)36(46)38(48)34(37(35)47)42-24-9-3-20(4-10-24)40(50)44-26-12-6-22-14-28(64(54,55)56)18-32(30(22)16-26)66(60,61)62/h1-18,41-42,45,48H,(H,43,49)(H,44,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	805	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Inhibition of human recombinant C-terminal FLAG-tagged autotaxin expressed in baculovirus-infected Sf9 cells assessed as FS-3 hydrolysis				J Med Chem 53: 3095-105 (2010) Article DOI: 10.1021/jm901718z BindingDB Entry DOI: 10.7270/Q2QZ2BXS
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233188 (CHEMBL4098521 | US11124490, Compound 3i) Show SMILES COC(=O)c1c(F)cc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc1F Show InChI InChI=1S/C19H16Cl2F2N2O6S/c1-30-19(27)17-14(22)6-10(7-15(17)23)24-18(26)11-8-16(13(21)9-12(11)20)32(28,29)25-2-4-31-5-3-25/h6-9H,2-5H2,1H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	864	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50366944 (Azovan Blue | Azovan sodium | EVANS BLUE) Show SMILES Cc1cc(ccc1N=Nc1ccc2c(cc(c(N)c2c1O)S([O-])(=O)=O)S([O-])(=O)=O)-c1ccc(N=Nc2ccc3c(cc(c(N)c3c2O)S([O-])(=O)=O)S([O-])(=O)=O)c(C)c1 |w:34.37,7.7| Show InChI InChI=1S/C34H28N6O14S4/c1-15-11-17(3-7-21(15)37-39-23-9-5-19-25(55(43,44)45)13-27(57(49,50)51)31(35)29(19)33(23)41)18-4-8-22(16(2)12-18)38-40-24-10-6-20-26(56(46,47)48)14-28(58(52,53)54)32(36)30(20)34(24)42/h3-14,41-42H,35-36H2,1-2H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54)/p-4	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	922	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Inhibition of human recombinant C-terminal FLAG-tagged autotaxin expressed in baculovirus-infected Sf9 cells assessed as FS-3 hydrolysis				J Med Chem 53: 3095-105 (2010) Article DOI: 10.1021/jm901718z BindingDB Entry DOI: 10.7270/Q2QZ2BXS
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233185 (CHEMBL4090985 | US11124490, Compound 25) Show SMILES Fc1cc(NC(=O)c2cc(NN3CCOCC3)c(Cl)cc2Cl)cc(F)c1F Show InChI InChI=1S/C17H14Cl2F3N3O2/c18-11-8-12(19)15(24-25-1-3-27-4-2-25)7-10(11)17(26)23-9-5-13(20)16(22)14(21)6-9/h5-8,24H,1-4H2,(H,23,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233175 (CHEMBL4072530) Show SMILES Fc1ccc(NCc2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc1F Show InChI InChI=1S/C17H16Cl2F2N2O3S/c18-13-9-14(19)17(27(24,25)23-3-5-26-6-4-23)7-11(13)10-22-12-1-2-15(20)16(21)8-12/h1-2,7-9,22H,3-6,10H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233167 (CHEMBL4091887 | US11124490, Compound 20) Show SMILES Fc1cccc(c1)S(=O)(=O)N(c1cc(c(Cl)cc1Cl)S(=O)(=O)N1CCOCC1)S(=O)(=O)c1cccc(F)c1 Show InChI InChI=1S/C22H18Cl2F2N2O7S3/c23-19-13-20(24)22(38(33,34)27-7-9-35-10-8-27)14-21(19)28(36(29,30)17-5-1-3-15(25)11-17)37(31,32)18-6-2-4-16(26)12-18/h1-6,11-14H,7-10H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233183 (CHEMBL4091756 | US11124490, Compound 3e) Show SMILES COc1cc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc(OC)c1OC Show InChI InChI=1S/C20H22Cl2N2O7S/c1-28-16-8-12(9-17(29-2)19(16)30-3)23-20(25)13-10-18(15(22)11-14(13)21)32(26,27)24-4-6-31-7-5-24/h8-11H,4-7H2,1-3H3,(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233186 (CHEMBL4070002 | US11124490, Compound 23) Show SMILES Fc1cc(NS(=O)(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc(F)c1F Show InChI InChI=1S/C16H13Cl2F3N2O5S2/c17-10-7-11(18)15(30(26,27)23-1-3-28-4-2-23)8-14(10)29(24,25)22-9-5-12(19)16(21)13(20)6-9/h5-8,22H,1-4H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233158 (CHEMBL4097621) Show SMILES COc1cc(Cl)c(cc1S(=O)(=O)N1CCOCC1)C(=O)Nc1cc(F)c(C(O)=O)c(F)c1 Show InChI InChI=1S/C19H17ClF2N2O7S/c1-30-15-9-12(20)11(8-16(15)32(28,29)24-2-4-31-5-3-24)18(25)23-10-6-13(21)17(19(26)27)14(22)7-10/h6-9H,2-5H2,1H3,(H,23,25)(H,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...				J Med Chem 60: 1309-1324 (2017) Article DOI: 10.1021/acs.jmedchem.6b01270 BindingDB Entry DOI: 10.7270/Q2K64MBD
					More data for this Ligand-Target Pair

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