| Reaction Details |
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 | Report a problem with these data |
| Target | Complement factor D |
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| Ligand | BDBM50236213 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1658835 (CHEMBL4008447) |
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| Kd | 500000±n/a nM |
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| Citation |  Vulpetti, A; Randl, S; Rüdisser, S; Ostermann, N; Erbel, P; Mac Sweeney, A; Zoller, T; Salem, B; Gerhartz, B; Cumin, F; Hommel, U; Dalvit, C; Lorthiois, E; Maibaum, J Structure-Based Library Design and Fragment Screening for the Identification of Reversible Complement Factor D Protease Inhibitors. J Med Chem60:1946-1958 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Complement factor D |
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| Name: | Complement factor D |
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| Synonyms: | Adipsin | C3 convertase activator | CFAD_HUMAN | CFD | DF | PFD | Properdin factor D |
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| Type: | Protein |
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| Mol. Mass.: | 27039.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00746 |
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| Residue: | 253 |
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| Sequence: | MHSWERLAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQW
VLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQL
SEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCN
RRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTR
VASYAAWIDSVLA
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| BDBM50236213 |
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| n/a |
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| Name | BDBM50236213 |
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| Synonyms: | 2-(3-Benzylureido)Benzoic Acid | CHEMBL561499 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H14N2O3 |
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| Mol. Mass. | 270.2833 |
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| SMILES | OC(=O)c1ccccc1NC(=O)NCc1ccccc1 |
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| Structure | 
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