| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1F |
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| Ligand | BDBM85195 |
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| Substrate/Competitor | n/a |
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| Ki | 6±n/a nM |
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| Comments | PDSP_1150 |
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| Citation |  Phebus, LA; Johnson, KW; Zgombick, JM; Gilbert, PJ; Van Belle, K; Mancuso, V; Nelson, DL; Calligaro, DO; Kiefer, AD; Branchek, TA; Flaugh, ME Characterization of LY344864 as a pharmacological tool to study 5-HT1F receptors: binding affinities, brain penetration and activity in the neurogenic dural inflammation model of migraine. Life Sci61:2117-26 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 1F |
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| Name: | 5-hydroxytryptamine receptor 1F |
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| Synonyms: | 5-HT-1F | 5-HT1F | 5-hydroxytryptamine receptor 1F | 5HT1F_HUMAN | HTR1EL | HTR1F | Serotonin (5-HT) receptor | Serotonin 1f (5-HT1f) receptor | Serotonin receptor 1F |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41724.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | 5-HT1F HTR1F HUMAN::P30939 |
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| Residue: | 366 |
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| Sequence: | MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANY
LICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALD
RYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIV
STIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKS
VSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILG
AFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQK
LVRCRC
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| BDBM85195 |
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| n/a |
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| Name | BDBM85195 |
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| Synonyms: | CAS_5311097 | LY 344864 | NSC_5311097 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22FN3O |
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| Mol. Mass. | 351.4173 |
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| SMILES | CN(C)C1CCc2[nH]c3ccc(NC(=O)c4ccc(F)cc4)cc3c2C1 |
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| Structure | 
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