Ki Summary

Reaction Details

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Target

Pyroglutamylated RF-amide peptide receptor

Ligand

BDBM86229

Substrate/Competitor

n/a

>10000±n/a nM

Comments

PDSP_7191

Citation

Jiang, Y; Luo, L; Gustafson, EL; Yadav, D; Laverty, M; Murgolo, N; Vassileva, G; Zeng, M; Laz, TM; Behan, J; Qiu, P; Wang, L; Wang, S; Bayne, M; Greene, J; Monsma, F; Zhang, FL Identification and characterization of a novel RF-amide peptide ligand for orphan G-protein-coupled receptor SP9155. J Biol Chem278:27652-7 (2003) [PubMed] Article

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Pyroglutamylated RF-amide peptide receptor

Name:

Pyroglutamylated RF-amide peptide receptor

Synonyms:

GPR103 | Pyroglutamylated RFamide peptide receptor | QRFPR | QRFPR_HUMAN

Type:

Enzyme Catalytic Domain

Mol. Mass.:

49508.46

Organism:

Homo sapiens (Human)

Description:

GPR103 0 HUMAN::Q96P65

Residue:

431

Sequence:

MQALNITPEQFSRLLRDHNLTREQFIALYRLRPLVYTPELPGRAKLALVLTGVLIFALAL
FGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQNISDNWLGGAFICKM
VPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLVAVIVGSPM
WHVQQLEIKYDFLYEKEHICCLEEWTSPVHQKIYTTFILVILFLLPLMVMLILYSKIGYE
LWIKKRVGDGSVLRTIHGKEMSKIARKKKRAVIMMVTVVALFAVCWAPFHVVHMMIEYSN
FEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNENFKKNVLSAVCYCIVNKTFSPAQ
RHGNSGITMMRKKAKFSLRENPVEETKGEAFSDGNIEVKLCEQTEEKKKLKRHLALFRSE
LAENSPLDSGH

BDBM86229

n/a

Name

BDBM86229

Synonyms:

YGGFMRF-amide

Type

Small organic molecule

Emp. Form.

C42H57N11O8S

Mol. Mass.

876.036

SMILES

[#6]-[#16]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6](-[#6]-c1ccccc1)-[#6](-[#7])=O |r|

Structure