| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 2 |
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| Ligand | BDBM50091652 |
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| Substrate/Competitor | n/a |
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| Ki | 2.1±n/a nM |
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| Comments | PDSP_1556 |
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| Citation |  Kakui, N; Tanaka, J; Tabata, Y; Asai, K; Masuda, N; Miyara, T; Nakatani, Y; Ohsawa, F; Nishikawa, N; Sugai, M; Suzuki, M; Aoki, K; Kitaguchi, H Pharmacological characterization and feeding-suppressive property of FMS586 [3-(5,6,7,8-tetrahydro-9-isopropyl-carbazol-3-yl)-1-methyl-1-(2-pyridin-4-yl-ethyl)-urea hydrochloride], a novel, selective, and orally active antagonist for neuropeptide Y Y5 receptor. J Pharmacol Exp Ther317:562-70 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Neuropeptide Y receptor type 2 |
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| Name: | Neuropeptide Y receptor type 2 |
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| Synonyms: | NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42734.65 |
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| Organism: | Homo sapiens (Human) |
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| Description: | NPY-Y2 NPY2R HUMAN::P49146 |
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| Residue: | 381 |
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| Sequence: | MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSI
ILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGP
VLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLA
SPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYT
RIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDL
KEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAK
KNLEVRKNSGPNDSFTEATNV
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| BDBM50091652 |
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| n/a |
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| Name | BDBM50091652 |
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| Synonyms: | CHEMBL269503 | PYY | PYY, rat | Peptide YY(PYY)(YPAKPEAPGEDASPEELSRYYASLAHYLNLVTRQRY) |
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| Type | Small organic molecule |
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| Emp. Form. | C190H287N53O58 |
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| Mol. Mass. | 4241.6321 |
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| SMILES | n/a |
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| Structure | 
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