Reaction Details |
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Target | Stromal cell-derived factor 1 |
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Ligand | BDBM50042947 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Tryptophan Fluorescence Assay |
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Temperature | 293.15±0 K |
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IC50 | 1.50e+5± 5.0e+4 nM |
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Citation | Hachet-Haas, M; Balabanian, K; Rohmer, F; Pons, F; Franchet, C; Lecat, S; Chow, KY; Dagher, R; Gizzi, P; Didier, B; Lagane, B; Kellenberger, E; Bonnet, D; Baleux, F; Haiech, J; Parmentier, M; Frossard, N; Arenzana-Seisdedos, F; Hibert, M; Galzi, JL Small neutralizing molecules to inhibit actions of the chemokine CXCL12. J Biol Chem283:23189-99 (2008) [PubMed] Article |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Stromal cell-derived factor 1 |
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Name: | Stromal cell-derived factor 1 |
Synonyms: | CXCL12 | Chemokine CXCL12 | SDF1 | SDF1A | SDF1B | SDF1_HUMAN |
Type: | Enzyme |
Mol. Mass.: | 10677.83 |
Organism: | Homo sapiens (Human) |
Description: | P48061 |
Residue: | 93 |
Sequence: | MNAKVVVVLVLVLTALCLSDGKPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIV
ARLKNNNRQVCIDPKLKWIQEYLEKALNKRFKM
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BDBM50042947 |
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n/a |
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Name | BDBM50042947 |
Synonyms: | 1-(4-Chloro-phenyl)-3-(4-hydroxy-3-methoxy-phenyl)-propenone | 1-(4-chlorophenyl)-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-one | 4'-chloro-3-methoxy-4-hydroxychalcone | CHEMBL126657 | Chalcone 4 |
Type | Small organic molecule |
Emp. Form. | C16H13ClO3 |
Mol. Mass. | 288.726 |
SMILES | COc1cc(\C=C\C(=O)c2ccc(Cl)cc2)ccc1O |
Structure |
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