Reaction Details |
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Target | Peptidyl-prolyl cis-trans isomerase A |
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Ligand | BDBM92916 |
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Substrate/Competitor | n/a |
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Meas. Tech. | PPIase Assay |
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pH | 7.8±n/a |
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Temperature | 278.15±n/a K |
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Ki | 1.0e+4± 2e+3 nM |
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Comments | extracted |
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Citation | Daum, S; Schumann, M; Mathea, S; Aumüller, T; Balsley, MA; Constant, SL; de Lacroix, BF; Kruska, F; Braun, M; Schiene-Fischer, C Isoform-specific inhibition of cyclophilins. Biochemistry48:6268-77 (2009) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Peptidyl-prolyl cis-trans isomerase A |
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Name: | Peptidyl-prolyl cis-trans isomerase A |
Synonyms: | CYPA | CYPA PPIase | Cyclophilin A | Cyclosporin A-binding protein | PPIA | PPIA_HUMAN | PPIase A | Peptidyl-prolyl cis-trans isomerase A | Rotamase A |
Type: | Protein |
Mol. Mass.: | 18015.32 |
Organism: | Homo sapiens (Human) |
Description: | P62937 |
Residue: | 165 |
Sequence: | MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGF
MCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTE
WLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE
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BDBM92916 |
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n/a |
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Name | BDBM92916 |
Synonyms: | Aryl 1-indanylketone, 5 |
Type | Small molecule |
Emp. Form. | C18H15F3O2 |
Mol. Mass. | 320.3057 |
SMILES | COc1ccc(cc1C(=O)C1CCc2ccccc12)C(F)(F)F |
Structure |
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