Reaction Details |
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Target | Peptidyl-prolyl cis-trans isomerase H |
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Ligand | BDBM92913 |
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Substrate/Competitor | n/a |
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Meas. Tech. | PPIase Assay |
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pH | 7.8±n/a |
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Temperature | 278.15±n/a K |
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Ki | >1.00e+5±n/a nM |
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Comments | extracted |
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Citation | Daum, S; Schumann, M; Mathea, S; Aumüller, T; Balsley, MA; Constant, SL; de Lacroix, BF; Kruska, F; Braun, M; Schiene-Fischer, C Isoform-specific inhibition of cyclophilins. Biochemistry48:6268-77 (2009) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Peptidyl-prolyl cis-trans isomerase H |
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Name: | Peptidyl-prolyl cis-trans isomerase H |
Synonyms: | CYP20 | CYPH | PPIH | PPIH_HUMAN | Peptidyl-prolyl cis-trans isomerase H (USA-Cyp) | Small nuclear ribonucleoprotein particle-specific cyclophilin H |
Type: | Protein |
Mol. Mass.: | 19211.45 |
Organism: | Homo sapiens (Human) |
Description: | O43447 |
Residue: | 177 |
Sequence: | MAVANSSPVNPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGEFRKDGVPIGY
KGSTFHRVIKDFMIQGGDFVNGDGTGVASIYRGPFADENFKLRHSAPGLLSMANSGPSTN
GCQFFITCSKCDWLDGKHVVFGKIIDGLLVMRKIENVPTGPNNKPKLPVVISQCGEM
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BDBM92913 |
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n/a |
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Name | BDBM92913 |
Synonyms: | Aryl 1-indanylketone, 2 |
Type | Small molecule |
Emp. Form. | C22H18FNO3 |
Mol. Mass. | 363.3816 |
SMILES | Nc1cc(F)cc(-c2ccc(O)c(c2)C(=O)C2CCc3ccccc23)c1O |
Structure |
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