| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase pim-1 |
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| Ligand | BDBM50299245 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | 5.7e+2±n/a nM |
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| Citation |  Anizon, F; Moreau, P; Prudhomme, M; Cohen, P; Aboab, B; Akue-Gedu, R; Rossignol, E Pyrrolo[2,3-a] carbazoles and use thereof as PIM kinase inhibitors US Patent US8481586 Publication Date 7/9/2013 |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase pim-1 |
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| Name: | Serine/threonine-protein kinase pim-1 |
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| Synonyms: | PIM-1 Kinase | PIM1 | PIM1_HUMAN | Proto-oncogene serine/threonine-protein kinase Pim-1 | Serine/threonine-protein kinase (PIM1) | Serine/threonine-protein kinase PIM | Serine/threonine-protein kinase PIM1 | Serine/threonine-protein kinase pim-1 (PIM1) |
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| Type: | Protein |
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| Mol. Mass.: | 35681.82 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P11309 |
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| Residue: | 313 |
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| Sequence: | MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSD
NLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLIL
ERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRG
ELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDI
PFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETA
EIHLHSLSPGPSK
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| BDBM50299245 |
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| n/a |
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| Name | BDBM50299245 |
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| Synonyms: | 7-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde | CHEMBL584195 | US8481586, 16 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H9BrN2O |
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| Mol. Mass. | 313.149 |
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| SMILES | Brc1ccc2[nH]c3c(ccc4c(C=O)c[nH]c34)c2c1 |
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| Structure | 
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