Found 174 hits with Last Name = 'prudhomme' and Initial = 'm' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50268249
(12,13-[6-Deoxy-6-amino-4-O-methyl-D-mannopyranosyl...)Show SMILES CO[C@@H]1[C@@H](CN)O[C@@H]2[C@H]([C@H]1O)n1c3ccccc3c3c4C(=O)NC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C27H22N4O5/c1-35-24-15(10-28)36-27-22(23(24)32)30-13-8-4-2-6-11(13)16-18-19(26(34)29-25(18)33)17-12-7-3-5-9-14(12)31(27)21(17)20(16)30/h2-9,15,22-24,27,32H,10,28H2,1H3,(H,29,33,34)/t15-,22+,23-,24-,27-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of GST-tagged human full-length CHK1 expressed in Sf9 cells |
Eur J Med Chem 44: 2234-8 (2009)
Article DOI: 10.1016/j.ejmech.2008.05.023
BindingDB Entry DOI: 10.7270/Q2XP74R2 |
More data for this
Ligand-Target Pair | 
3D Structure (docked) |
Serine/threonine-protein kinase pim-3
(Homo sapiens (Human)) | BDBM50299249
(1,10-Dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde...)Show InChI InChI=1S/C15H10N2O/c18-8-9-7-16-14-10(9)5-6-12-11-3-1-2-4-13(11)17-15(12)14/h1-8,16-17H | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Clermont Universit£
Curated by ChEMBL
| Assay Description
Inhibition of Pim-3 |
J Med Chem 52: 6369-81 (2009)
Article DOI: 10.1021/jm901018f
BindingDB Entry DOI: 10.7270/Q23F4PPS |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-3
(Homo sapiens (Human)) | BDBM50299249
(1,10-Dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde...)Show InChI InChI=1S/C15H10N2O/c18-8-9-7-16-14-10(9)5-6-12-11-3-1-2-4-13(11)17-15(12)14/h1-8,16-17H | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| US Patent
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II
US Patent
| Assay Description
Inhibition assay using PIM-1, PIM-2 and PIM-3. |
US Patent US8481586 (2013)
BindingDB Entry DOI: 10.7270/Q2ZC81GT |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50216159
(5-hydroxy-pyrrolo[3',4':5,6]indolizino[8,7-b]indol...)Show InChI InChI=1S/C16H9N3O3/c20-7-3-4-9-8(6-7)11-12-14(16(22)18-15(12)21)19-5-1-2-10(19)13(11)17-9/h1-6,17,20H,(H,18,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 |
Bioorg Med Chem 15: 5965-80 (2007)
Article DOI: 10.1016/j.bmc.2007.05.073
BindingDB Entry DOI: 10.7270/Q2KW5FR0 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50220067
(11H-2,5,11-triaza-benzo[a]trindene-1,3,4,6-tetraon...)Show SMILES O=c1[nH]c(=O)c2c1c1[nH]c3ccccc3c1c1c2c(=O)[nH]c1=O Show InChI InChI=1S/C16H7N3O4/c20-13-8-7-5-3-1-2-4-6(5)17-12(7)11-10(9(8)14(21)18-13)15(22)19-16(11)23/h1-4,17H,(H,18,20,21)(H,19,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 |
Eur J Med Chem 43: 282-92 (2008)
Article DOI: 10.1016/j.ejmech.2007.03.026
BindingDB Entry DOI: 10.7270/Q2H70FKP |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50220067
(11H-2,5,11-triaza-benzo[a]trindene-1,3,4,6-tetraon...)Show SMILES O=c1[nH]c(=O)c2c1c1[nH]c3ccccc3c1c1c2c(=O)[nH]c1=O Show InChI InChI=1S/C16H7N3O4/c20-13-8-7-5-3-1-2-4-6(5)17-12(7)11-10(9(8)14(21)18-13)15(22)19-16(11)23/h1-4,17H,(H,18,20,21)(H,19,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 |
Bioorg Med Chem 16: 4419-30 (2008)
Article DOI: 10.1016/j.bmc.2008.02.061
BindingDB Entry DOI: 10.7270/Q24Q7VV9 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50220067
(11H-2,5,11-triaza-benzo[a]trindene-1,3,4,6-tetraon...)Show SMILES O=c1[nH]c(=O)c2c1c1[nH]c3ccccc3c1c1c2c(=O)[nH]c1=O Show InChI InChI=1S/C16H7N3O4/c20-13-8-7-5-3-1-2-4-6(5)17-12(7)11-10(9(8)14(21)18-13)15(22)19-16(11)23/h1-4,17H,(H,18,20,21)(H,19,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 expressed in Sf9 cells |
J Med Chem 50: 4669-80 (2007)
Article DOI: 10.1021/jm070664k
BindingDB Entry DOI: 10.7270/Q2P55N7F |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50220064
(4,7,11-trihydroxybenzo[a]pyrrolo[3,4-c]carbazole-1...)Show SMILES Oc1ccc2[nH]c3c(c4C(=O)NC(=O)c4c4c(O)ccc(O)c34)c2c1 Show InChI InChI=1S/C18H10N2O5/c21-6-1-2-8-7(5-6)11-14-15(18(25)20-17(14)24)12-9(22)3-4-10(23)13(12)16(11)19-8/h1-5,19,21-23H,(H,20,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 expressed in Sf9 cells |
J Med Chem 50: 4669-80 (2007)
Article DOI: 10.1021/jm070664k
BindingDB Entry DOI: 10.7270/Q2P55N7F |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50376170
(CHEMBL265446)Show InChI InChI=1S/C16H9N3O3/c20-14-10-7(5-17-14)13-9(6-3-1-2-4-8(6)18-13)11-12(10)16(22)19-15(11)21/h1-4,18H,5H2,(H,17,20)(H,19,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 |
Bioorg Med Chem 16: 4419-30 (2008)
Article DOI: 10.1016/j.bmc.2008.02.061
BindingDB Entry DOI: 10.7270/Q24Q7VV9 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50216171
(CHEMBL393545 | pyrrolo[3',4':5,6]indolizino[8,7-b]...)Show InChI InChI=1S/C16H9N3O2/c20-15-12-11-8-4-1-2-5-9(8)17-13(11)10-6-3-7-19(10)14(12)16(21)18-15/h1-7,17H,(H,18,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 |
Bioorg Med Chem 15: 5965-80 (2007)
Article DOI: 10.1016/j.bmc.2007.05.073
BindingDB Entry DOI: 10.7270/Q2KW5FR0 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50220072
(11-hydroxybenzo[a]pyrrolo[3,4-c]carbazole-1,3,4,7(...)Show SMILES Oc1ccc2nc3c(c2c1)c1c(c2c3c(O)ccc2=O)c(=O)[nH]c1=O Show InChI InChI=1S/C18H8N2O5/c21-6-1-2-8-7(5-6)11-14-15(18(25)20-17(14)24)12-9(22)3-4-10(23)13(12)16(11)19-8/h1-5,21,23H,(H,20,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 expressed in Sf9 cells |
J Med Chem 50: 4669-80 (2007)
Article DOI: 10.1021/jm070664k
BindingDB Entry DOI: 10.7270/Q2P55N7F |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-3
(Homo sapiens (Human)) | BDBM50299245
(7-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carb...)Show InChI InChI=1S/C15H9BrN2O/c16-9-1-4-13-12(5-9)11-3-2-10-8(7-19)6-17-14(10)15(11)18-13/h1-7,17-18H | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| US Patent
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II
US Patent
| Assay Description
Inhibition assay using PIM-1, PIM-2 and PIM-3. |
US Patent US8481586 (2013)
BindingDB Entry DOI: 10.7270/Q2ZC81GT |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-3
(Homo sapiens (Human)) | BDBM50299245
(7-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carb...)Show InChI InChI=1S/C15H9BrN2O/c16-9-1-4-13-12(5-9)11-3-2-10-8(7-19)6-17-14(10)15(11)18-13/h1-7,17-18H | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Clermont Universit£
Curated by ChEMBL
| Assay Description
Inhibition of Pim-3 |
J Med Chem 52: 6369-81 (2009)
Article DOI: 10.1021/jm901018f
BindingDB Entry DOI: 10.7270/Q23F4PPS |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50220066
(6,7-dihydro-1H-cyclopenta[a]pyrrolo[3,4-c]carbazol...)Show InChI InChI=1S/C17H10N2O3/c20-10-6-5-8-11(10)13-14(17(22)19-16(13)21)12-7-3-1-2-4-9(7)18-15(8)12/h1-4,18H,5-6H2,(H,19,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 expressed in Sf9 cells |
J Med Chem 50: 4669-80 (2007)
Article DOI: 10.1021/jm070664k
BindingDB Entry DOI: 10.7270/Q2P55N7F |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50236805
(4,5-dihydro-11H-2,5,11-triaza-benzo[a]trindene-1,3...)Show InChI InChI=1S/C16H9N3O3/c20-14-10-7(5-17-14)11-12(16(22)19-15(11)21)13-9(10)6-3-1-2-4-8(6)18-13/h1-4,18H,5H2,(H,17,20)(H,19,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 |
Eur J Med Chem 43: 282-92 (2008)
Article DOI: 10.1016/j.ejmech.2007.03.026
BindingDB Entry DOI: 10.7270/Q2H70FKP |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50236805
(4,5-dihydro-11H-2,5,11-triaza-benzo[a]trindene-1,3...)Show InChI InChI=1S/C16H9N3O3/c20-14-10-7(5-17-14)11-12(16(22)19-15(11)21)13-9(10)6-3-1-2-4-8(6)18-13/h1-4,18H,5H2,(H,17,20)(H,19,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 |
Bioorg Med Chem 16: 4419-30 (2008)
Article DOI: 10.1016/j.bmc.2008.02.061
BindingDB Entry DOI: 10.7270/Q24Q7VV9 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50216161
(5-bromo-pyrrolo[3',4':51,3-(2H,8H)-dione,6]indoliz...)Show InChI InChI=1S/C16H8BrN3O2/c17-7-3-4-9-8(6-7)11-12-14(16(22)19-15(12)21)20-5-1-2-10(20)13(11)18-9/h1-6,18H,(H,19,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 |
Bioorg Med Chem 15: 5965-80 (2007)
Article DOI: 10.1016/j.bmc.2007.05.073
BindingDB Entry DOI: 10.7270/Q2KW5FR0 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50216165
(1,11-dihydro-1,3,5,11-tetraaza-benzo[a]trindene-4,...)Show InChI InChI=1S/C15H8N4O2/c20-14-9-8-6-3-1-2-4-7(6)18-12(8)13-11(16-5-17-13)10(9)15(21)19-14/h1-5,18H,(H,16,17)(H,19,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 |
Eur J Med Chem 43: 282-92 (2008)
Article DOI: 10.1016/j.ejmech.2007.03.026
BindingDB Entry DOI: 10.7270/Q2H70FKP |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50216165
(1,11-dihydro-1,3,5,11-tetraaza-benzo[a]trindene-4,...)Show InChI InChI=1S/C15H8N4O2/c20-14-9-8-6-3-1-2-4-7(6)18-12(8)13-11(16-5-17-13)10(9)15(21)19-14/h1-5,18H,(H,16,17)(H,19,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 |
Bioorg Med Chem 15: 5965-80 (2007)
Article DOI: 10.1016/j.bmc.2007.05.073
BindingDB Entry DOI: 10.7270/Q2KW5FR0 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50216165
(1,11-dihydro-1,3,5,11-tetraaza-benzo[a]trindene-4,...)Show InChI InChI=1S/C15H8N4O2/c20-14-9-8-6-3-1-2-4-7(6)18-12(8)13-11(16-5-17-13)10(9)15(21)19-14/h1-5,18H,(H,16,17)(H,19,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 81 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 expressed in Sf9 cells |
J Med Chem 50: 4669-80 (2007)
Article DOI: 10.1021/jm070664k
BindingDB Entry DOI: 10.7270/Q2P55N7F |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50216165
(1,11-dihydro-1,3,5,11-tetraaza-benzo[a]trindene-4,...)Show InChI InChI=1S/C15H8N4O2/c20-14-9-8-6-3-1-2-4-7(6)18-12(8)13-11(16-5-17-13)10(9)15(21)19-14/h1-5,18H,(H,16,17)(H,19,20,21) | PDB
MMDB
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| n/a | n/a | 81 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 |
Bioorg Med Chem 16: 4419-30 (2008)
Article DOI: 10.1016/j.bmc.2008.02.061
BindingDB Entry DOI: 10.7270/Q24Q7VV9 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50216163
(5-chloro-pyrrolo[3',4':5,6]indolizino[8,7-b]indole...)Show InChI InChI=1S/C16H8ClN3O2/c17-7-3-4-9-8(6-7)11-12-14(16(22)19-15(12)21)20-5-1-2-10(20)13(11)18-9/h1-6,18H,(H,19,21,22) | PDB
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Reactome pathway
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| n/a | n/a | 89 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 |
Bioorg Med Chem 15: 5965-80 (2007)
Article DOI: 10.1016/j.bmc.2007.05.073
BindingDB Entry DOI: 10.7270/Q2KW5FR0 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50216157
(11H-2,5,11,11b-Tetraaza-benzo[a]trindene-4,6-dione...)Show InChI InChI=1S/C15H8N4O2/c20-14-11-9-5-16-6-19(9)13-10(12(11)15(21)18-14)7-3-1-2-4-8(7)17-13/h1-6,17H,(H,18,20,21) | PDB
MMDB
Reactome pathway
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B.MOAD
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CHEMBL
PC cid
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| Article
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| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 |
Bioorg Med Chem 16: 4419-30 (2008)
Article DOI: 10.1016/j.bmc.2008.02.061
BindingDB Entry DOI: 10.7270/Q24Q7VV9 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50220075
(11-methylbenzo[a]pyrrolo[3,4-c]carbazole-1,3,4,7(2...)Show SMILES Cc1ccc2nc3c(c2c1)c1c(c2c3c(O)ccc2=O)c(=O)[nH]c1=O Show InChI InChI=1S/C19H10N2O4/c1-7-2-3-9-8(6-7)12-15-16(19(25)21-18(15)24)13-10(22)4-5-11(23)14(13)17(12)20-9/h2-6,23H,1H3,(H,21,24,25) | PDB
MMDB
Reactome pathway
KEGG
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| n/a | n/a | 107 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 expressed in Sf9 cells |
J Med Chem 50: 4669-80 (2007)
Article DOI: 10.1021/jm070664k
BindingDB Entry DOI: 10.7270/Q2P55N7F |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human)) | BDBM50299249
(1,10-Dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde...)Show InChI InChI=1S/C15H10N2O/c18-8-9-7-16-14-10(9)5-6-12-11-3-1-2-4-13(11)17-15(12)14/h1-8,16-17H | PDB
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| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Clermont Universit£
Curated by ChEMBL
| Assay Description
Inhibition of Pim-1 |
J Med Chem 52: 6369-81 (2009)
Article DOI: 10.1021/jm901018f
BindingDB Entry DOI: 10.7270/Q23F4PPS |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human)) | BDBM50299249
(1,10-Dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde...)Show InChI InChI=1S/C15H10N2O/c18-8-9-7-16-14-10(9)5-6-12-11-3-1-2-4-13(11)17-15(12)14/h1-8,16-17H | PDB
MMDB
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| US Patent
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II
US Patent
| Assay Description
Inhibition assay using PIM-1, PIM-2 and PIM-3. |
US Patent US8481586 (2013)
BindingDB Entry DOI: 10.7270/Q2ZC81GT |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50220065
(4,7-dihydroxy-11-methylbenzo[a]pyrrolo[3,4-c]carba...)Show SMILES Cc1ccc2[nH]c3c(c4C(=O)NC(=O)c4c4c(O)ccc(O)c34)c2c1 Show InChI InChI=1S/C19H12N2O4/c1-7-2-3-9-8(6-7)12-15-16(19(25)21-18(15)24)13-10(22)4-5-11(23)14(13)17(12)20-9/h2-6,20,22-23H,1H3,(H,21,24,25) | PDB
MMDB
Reactome pathway
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| n/a | n/a | 161 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 expressed in Sf9 cells |
J Med Chem 50: 4669-80 (2007)
Article DOI: 10.1021/jm070664k
BindingDB Entry DOI: 10.7270/Q2P55N7F |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-3
(Homo sapiens (Human)) | BDBM50299247
(1-(1,10-Dihydropyrrolo[2,3-a]carbazol-3-yl)-2,2,2-...)Show SMILES FC(F)(F)C(=O)c1c[nH]c2c1ccc1c3ccccc3[nH]c21 Show InChI InChI=1S/C16H9F3N2O/c17-16(18,19)15(22)11-7-20-13-10(11)6-5-9-8-3-1-2-4-12(8)21-14(9)13/h1-7,20-21H | KEGG
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| US Patent
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II
US Patent
| Assay Description
Inhibition assay using PIM-1, PIM-2 and PIM-3. |
US Patent US8481586 (2013)
BindingDB Entry DOI: 10.7270/Q2ZC81GT |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-3
(Homo sapiens (Human)) | BDBM50299247
(1-(1,10-Dihydropyrrolo[2,3-a]carbazol-3-yl)-2,2,2-...)Show SMILES FC(F)(F)C(=O)c1c[nH]c2c1ccc1c3ccccc3[nH]c21 Show InChI InChI=1S/C16H9F3N2O/c17-16(18,19)15(22)11-7-20-13-10(11)6-5-9-8-3-1-2-4-12(8)21-14(9)13/h1-7,20-21H | KEGG
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| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Clermont Universit£
Curated by ChEMBL
| Assay Description
Inhibition of Pim-3 |
J Med Chem 52: 6369-81 (2009)
Article DOI: 10.1021/jm901018f
BindingDB Entry DOI: 10.7270/Q23F4PPS |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-3
(Homo sapiens (Human)) | BDBM50299250
(7-(2,4-Difluorophenyl)-1,10-dihydropyrrolo[2,3-a]c...)Show SMILES Fc1ccc(c(F)c1)-c1ccc2[nH]c3c(ccc4c(C=O)c[nH]c34)c2c1 Show InChI InChI=1S/C21H12F2N2O/c22-13-2-3-14(18(23)8-13)11-1-6-19-17(7-11)16-5-4-15-12(10-26)9-24-20(15)21(16)25-19/h1-10,24-25H | KEGG
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| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Clermont Universit£
Curated by ChEMBL
| Assay Description
Inhibition of Pim-3 |
J Med Chem 52: 6369-81 (2009)
Article DOI: 10.1021/jm901018f
BindingDB Entry DOI: 10.7270/Q23F4PPS |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-3
(Homo sapiens (Human)) | BDBM50299250
(7-(2,4-Difluorophenyl)-1,10-dihydropyrrolo[2,3-a]c...)Show SMILES Fc1ccc(c(F)c1)-c1ccc2[nH]c3c(ccc4c(C=O)c[nH]c34)c2c1 Show InChI InChI=1S/C21H12F2N2O/c22-13-2-3-14(18(23)8-13)11-1-6-19-17(7-11)16-5-4-15-12(10-26)9-24-20(15)21(16)25-19/h1-10,24-25H | KEGG
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| CHEMBL
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UniChem
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| US Patent
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II
US Patent
| Assay Description
Inhibition assay using PIM-1, PIM-2 and PIM-3. |
US Patent US8481586 (2013)
BindingDB Entry DOI: 10.7270/Q2ZC81GT |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-3
(Homo sapiens (Human)) | BDBM50299248
(1,10-Dihydropyrrolo[2,3-a]carbazole-3-carboxamide ...)Show InChI InChI=1S/C15H11N3O/c16-15(19)11-7-17-13-10(11)6-5-9-8-3-1-2-4-12(8)18-14(9)13/h1-7,17-18H,(H2,16,19) | KEGG
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| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Clermont Universit£
Curated by ChEMBL
| Assay Description
Inhibition of Pim-3 |
J Med Chem 52: 6369-81 (2009)
Article DOI: 10.1021/jm901018f
BindingDB Entry DOI: 10.7270/Q23F4PPS |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-3
(Homo sapiens (Human)) | BDBM50299248
(1,10-Dihydropyrrolo[2,3-a]carbazole-3-carboxamide ...)Show InChI InChI=1S/C15H11N3O/c16-15(19)11-7-17-13-10(11)6-5-9-8-3-1-2-4-12(8)18-14(9)13/h1-7,17-18H,(H2,16,19) | KEGG
UniProtKB/SwissProt
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AffyNet
| CHEMBL
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PC sid
UniChem
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| US Patent
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II
US Patent
| Assay Description
Inhibition assay using PIM-1, PIM-2 and PIM-3. |
US Patent US8481586 (2013)
BindingDB Entry DOI: 10.7270/Q2ZC81GT |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50251213
(6H-2-N-hydroxymethyl-5-ethoxycarbonyl-pyrrolo-[3,4...)Show SMILES CCOC(=O)c1cc2C(=O)N(CO)C(=O)c2c2c3ccccc3[nH]c12 Show InChI InChI=1S/C18H14N2O5/c1-2-25-18(24)11-7-10-14(17(23)20(8-21)16(10)22)13-9-5-3-4-6-12(9)19-15(11)13/h3-7,19,21H,2,8H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
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| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 |
Eur J Med Chem 43: 282-92 (2008)
Article DOI: 10.1016/j.ejmech.2007.03.026
BindingDB Entry DOI: 10.7270/Q2H70FKP |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50220074
(CHEMBL243930 | benzo[a]pyrrolo[3,4-c]carbazole-1,3...)Show SMILES Oc1ccc(=O)c2c3c(c4c5ccccc5nc4c12)c(=O)[nH]c3=O Show InChI InChI=1S/C18H8N2O4/c21-9-5-6-10(22)13-12(9)15-14(17(23)20-18(15)24)11-7-3-1-2-4-8(7)19-16(11)13/h1-6,22H,(H,20,23,24) | PDB
MMDB
Reactome pathway
KEGG
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UniChem
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PubMed
| n/a | n/a | 269 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 expressed in Sf9 cells |
J Med Chem 50: 4669-80 (2007)
Article DOI: 10.1021/jm070664k
BindingDB Entry DOI: 10.7270/Q2P55N7F |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50220074
(CHEMBL243930 | benzo[a]pyrrolo[3,4-c]carbazole-1,3...)Show SMILES Oc1ccc(=O)c2c3c(c4c5ccccc5nc4c12)c(=O)[nH]c3=O Show InChI InChI=1S/C18H8N2O4/c21-9-5-6-10(22)13-12(9)15-14(17(23)20-18(15)24)11-7-3-1-2-4-8(7)19-16(11)13/h1-6,22H,(H,20,23,24) | PDB
MMDB
Reactome pathway
KEGG
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| CHEMBL
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PC sid
UniChem
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PubMed
| n/a | n/a | 269 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 |
Bioorg Med Chem 16: 4419-30 (2008)
Article DOI: 10.1016/j.bmc.2008.02.061
BindingDB Entry DOI: 10.7270/Q24Q7VV9 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50220068
(4,7-dihydroxybenzo[a]pyrrolo[3,4-c]carbazole-1,3(2...)Show SMILES Oc1ccc(O)c2c3[nH]c4ccccc4c3c3C(=O)NC(=O)c3c12 Show InChI InChI=1S/C18H10N2O4/c21-9-5-6-10(22)13-12(9)15-14(17(23)20-18(15)24)11-7-3-1-2-4-8(7)19-16(11)13/h1-6,19,21-22H,(H,20,23,24) | PDB
MMDB
Reactome pathway
KEGG
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| CHEMBL
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 311 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 expressed in Sf9 cells |
J Med Chem 50: 4669-80 (2007)
Article DOI: 10.1021/jm070664k
BindingDB Entry DOI: 10.7270/Q2P55N7F |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50220068
(4,7-dihydroxybenzo[a]pyrrolo[3,4-c]carbazole-1,3(2...)Show SMILES Oc1ccc(O)c2c3[nH]c4ccccc4c3c3C(=O)NC(=O)c3c12 Show InChI InChI=1S/C18H10N2O4/c21-9-5-6-10(22)13-12(9)15-14(17(23)20-18(15)24)11-7-3-1-2-4-8(7)19-16(11)13/h1-6,19,21-22H,(H,20,23,24) | PDB
MMDB
Reactome pathway
KEGG
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| n/a | n/a | 311 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 |
Bioorg Med Chem 16: 4419-30 (2008)
Article DOI: 10.1016/j.bmc.2008.02.061
BindingDB Entry DOI: 10.7270/Q24Q7VV9 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50216165
(1,11-dihydro-1,3,5,11-tetraaza-benzo[a]trindene-4,...)Show InChI InChI=1S/C15H8N4O2/c20-14-9-8-6-3-1-2-4-7(6)18-12(8)13-11(16-5-17-13)10(9)15(21)19-14/h1-5,18H,(H,16,17)(H,19,20,21) | PDB
MMDB
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| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of Src |
J Med Chem 50: 4669-80 (2007)
Article DOI: 10.1021/jm070664k
BindingDB Entry DOI: 10.7270/Q2P55N7F |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50251201
(6,11-Dihydro-5H-2,5,11-triaza-benzo[a]trindene-1,3...)Show InChI InChI=1S/C16H9N3O3/c20-14-10-7(5-17-14)9-6-3-1-2-4-8(6)18-13(9)12-11(10)15(21)19-16(12)22/h1-4,18H,5H2,(H,17,20)(H,19,21,22) | PDB
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| n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 |
Eur J Med Chem 43: 282-92 (2008)
Article DOI: 10.1016/j.ejmech.2007.03.026
BindingDB Entry DOI: 10.7270/Q2H70FKP |
More data for this
Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50295872
(5-Iodo-4-(1-Methyl-1H-indol-3-yl)pyrimidin-2-amine...)Show InChI InChI=1S/C13H11IN4/c1-18-7-9(8-4-2-3-5-11(8)18)12-10(14)6-16-13(15)17-12/h2-7H,1H3,(H2,15,16,17) | PDB
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| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Clermont Universit£
Curated by ChEMBL
| Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli |
Bioorg Med Chem 17: 4420-4 (2009)
Article DOI: 10.1016/j.bmc.2009.05.017
BindingDB Entry DOI: 10.7270/Q2639PSH |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50216157
(11H-2,5,11,11b-Tetraaza-benzo[a]trindene-4,6-dione...)Show InChI InChI=1S/C15H8N4O2/c20-14-11-9-5-16-6-19(9)13-10(12(11)15(21)18-14)7-3-1-2-4-8(7)17-13/h1-6,17H,(H,18,20,21) | PDB
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| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 expressed in Sf9 cells |
J Med Chem 50: 4669-80 (2007)
Article DOI: 10.1021/jm070664k
BindingDB Entry DOI: 10.7270/Q2P55N7F |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50216157
(11H-2,5,11,11b-Tetraaza-benzo[a]trindene-4,6-dione...)Show InChI InChI=1S/C15H8N4O2/c20-14-11-9-5-16-6-19(9)13-10(12(11)15(21)18-14)7-3-1-2-4-8(7)17-13/h1-6,17H,(H,18,20,21) | PDB
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| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 |
Bioorg Med Chem 15: 5965-80 (2007)
Article DOI: 10.1016/j.bmc.2007.05.073
BindingDB Entry DOI: 10.7270/Q2KW5FR0 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-3
(Homo sapiens (Human)) | BDBM50299246
(7-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole | CHEM...)Show InChI InChI=1S/C14H9BrN2/c15-9-2-4-12-11(7-9)10-3-1-8-5-6-16-13(8)14(10)17-12/h1-7,16-17H | KEGG
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| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II
US Patent
| Assay Description
Inhibition assay using PIM-1, PIM-2 and PIM-3. |
US Patent US8481586 (2013)
BindingDB Entry DOI: 10.7270/Q2ZC81GT |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50216157
(11H-2,5,11,11b-Tetraaza-benzo[a]trindene-4,6-dione...)Show InChI InChI=1S/C15H8N4O2/c20-14-11-9-5-16-6-19(9)13-10(12(11)15(21)18-14)7-3-1-2-4-8(7)17-13/h1-6,17H,(H,18,20,21) | PDB
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| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description
Inhibition of human Chk1 |
Eur J Med Chem 43: 282-92 (2008)
Article DOI: 10.1016/j.ejmech.2007.03.026
BindingDB Entry DOI: 10.7270/Q2H70FKP |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-3
(Homo sapiens (Human)) | BDBM50299246
(7-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole | CHEM...)Show InChI InChI=1S/C14H9BrN2/c15-9-2-4-12-11(7-9)10-3-1-8-5-6-16-13(8)14(10)17-12/h1-7,16-17H | KEGG
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Clermont Universit£
Curated by ChEMBL
| Assay Description
Inhibition of Pim-3 |
J Med Chem 52: 6369-81 (2009)
Article DOI: 10.1021/jm901018f
BindingDB Entry DOI: 10.7270/Q23F4PPS |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-2
(Homo sapiens (Human)) | BDBM50299249
(1,10-Dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde...)Show InChI InChI=1S/C15H10N2O/c18-8-9-7-16-14-10(9)5-6-12-11-3-1-2-4-13(11)17-15(12)14/h1-8,16-17H | PDB
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| n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II
US Patent
| Assay Description
Inhibition assay using PIM-1, PIM-2 and PIM-3. |
US Patent US8481586 (2013)
BindingDB Entry DOI: 10.7270/Q2ZC81GT |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-2
(Homo sapiens (Human)) | BDBM50299249
(1,10-Dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde...)Show InChI InChI=1S/C15H10N2O/c18-8-9-7-16-14-10(9)5-6-12-11-3-1-2-4-13(11)17-15(12)14/h1-8,16-17H | PDB
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| n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a | n/a |
Clermont Universit£
Curated by ChEMBL
| Assay Description
Inhibition of Pim-2 |
J Med Chem 52: 6369-81 (2009)
Article DOI: 10.1021/jm901018f
BindingDB Entry DOI: 10.7270/Q23F4PPS |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human)) | BDBM50299245
(7-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carb...)Show InChI InChI=1S/C15H9BrN2O/c16-9-1-4-13-12(5-9)11-3-2-10-8(7-19)6-17-14(10)15(11)18-13/h1-7,17-18H | PDB
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| n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | n/a |
Clermont Universit£
Curated by ChEMBL
| Assay Description
Inhibition of Pim-1 |
J Med Chem 52: 6369-81 (2009)
Article DOI: 10.1021/jm901018f
BindingDB Entry DOI: 10.7270/Q23F4PPS |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human)) | BDBM50299245
(7-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carb...)Show InChI InChI=1S/C15H9BrN2O/c16-9-1-4-13-12(5-9)11-3-2-10-8(7-19)6-17-14(10)15(11)18-13/h1-7,17-18H | PDB
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| US Patent
| n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II
US Patent
| Assay Description
Inhibition assay using PIM-1, PIM-2 and PIM-3. |
US Patent US8481586 (2013)
BindingDB Entry DOI: 10.7270/Q2ZC81GT |
More data for this
Ligand-Target Pair | |
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