Compile Data Set for Download or QSAR

Found 53 hits with Last Name = 'akue-gedu' and Initial = 'r'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50299249 (1,10-Dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde...) Show SMILES O=Cc1c[nH]c2c1ccc1c3ccccc3[nH]c21 Show InChI InChI=1S/C15H10N2O/c18-8-9-7-16-14-10(9)5-6-12-11-3-1-2-4-13(11)17-15(12)14/h1-8,16-17H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II US Patent					Assay Description Inhibition assay using PIM-1, PIM-2 and PIM-3.				US Patent US8481586 (2013) BindingDB Entry DOI: 10.7270/Q2ZC81GT
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50299245 (7-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carb...) Show SMILES Brc1ccc2[nH]c3c(ccc4c(C=O)c[nH]c34)c2c1 Show InChI InChI=1S/C15H9BrN2O/c16-9-1-4-13-12(5-9)11-3-2-10-8(7-19)6-17-14(10)15(11)18-13/h1-7,17-18H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II US Patent					Assay Description Inhibition assay using PIM-1, PIM-2 and PIM-3.				US Patent US8481586 (2013) BindingDB Entry DOI: 10.7270/Q2ZC81GT
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50299249 (1,10-Dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde...) Show SMILES O=Cc1c[nH]c2c1ccc1c3ccccc3[nH]c21 Show InChI InChI=1S/C15H10N2O/c18-8-9-7-16-14-10(9)5-6-12-11-3-1-2-4-13(11)17-15(12)14/h1-8,16-17H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II US Patent					Assay Description Inhibition assay using PIM-1, PIM-2 and PIM-3.				US Patent US8481586 (2013) BindingDB Entry DOI: 10.7270/Q2ZC81GT
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50299247 (1-(1,10-Dihydropyrrolo[2,3-a]carbazol-3-yl)-2,2,2-...) Show SMILES FC(F)(F)C(=O)c1c[nH]c2c1ccc1c3ccccc3[nH]c21 Show InChI InChI=1S/C16H9F3N2O/c17-16(18,19)15(22)11-7-20-13-10(11)6-5-9-8-3-1-2-4-12(8)21-14(9)13/h1-7,20-21H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II US Patent					Assay Description Inhibition assay using PIM-1, PIM-2 and PIM-3.				US Patent US8481586 (2013) BindingDB Entry DOI: 10.7270/Q2ZC81GT
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50299250 (7-(2,4-Difluorophenyl)-1,10-dihydropyrrolo[2,3-a]c...) Show SMILES Fc1ccc(c(F)c1)-c1ccc2[nH]c3c(ccc4c(C=O)c[nH]c34)c2c1 Show InChI InChI=1S/C21H12F2N2O/c22-13-2-3-14(18(23)8-13)11-1-6-19-17(7-11)16-5-4-15-12(10-26)9-24-20(15)21(16)25-19/h1-10,24-25H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II US Patent					Assay Description Inhibition assay using PIM-1, PIM-2 and PIM-3.				US Patent US8481586 (2013) BindingDB Entry DOI: 10.7270/Q2ZC81GT
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50299248 (1,10-Dihydropyrrolo[2,3-a]carbazole-3-carboxamide ...) Show SMILES NC(=O)c1c[nH]c2c1ccc1c3ccccc3[nH]c21 Show InChI InChI=1S/C15H11N3O/c16-15(19)11-7-17-13-10(11)6-5-9-8-3-1-2-4-12(8)18-14(9)13/h1-7,17-18H,(H2,16,19)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	US Patent	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II US Patent					Assay Description Inhibition assay using PIM-1, PIM-2 and PIM-3.				US Patent US8481586 (2013) BindingDB Entry DOI: 10.7270/Q2ZC81GT
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50295872 (5-Iodo-4-(1-Methyl-1H-indol-3-yl)pyrimidin-2-amine...) Show SMILES Cn1cc(-c2nc(N)ncc2I)c2ccccc12 Show InChI InChI=1S/C13H11IN4/c1-18-7-9(8-4-2-3-5-11(8)18)12-10(14)6-16-13(15)17-12/h2-7H,1H3,(H2,15,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A expressed in Escherichia coli				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50299246 (7-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole | CHEM...) Show SMILES Brc1ccc2[nH]c3c(ccc4cc[nH]c34)c2c1 Show InChI InChI=1S/C14H9BrN2/c15-9-2-4-12-11(7-9)10-3-1-8-5-6-16-13(8)14(10)17-12/h1-7,16-17H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II US Patent					Assay Description Inhibition assay using PIM-1, PIM-2 and PIM-3.				US Patent US8481586 (2013) BindingDB Entry DOI: 10.7270/Q2ZC81GT
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50299249 (1,10-Dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde...) Show SMILES O=Cc1c[nH]c2c1ccc1c3ccccc3[nH]c21 Show InChI InChI=1S/C15H10N2O/c18-8-9-7-16-14-10(9)5-6-12-11-3-1-2-4-13(11)17-15(12)14/h1-8,16-17H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II US Patent					Assay Description Inhibition assay using PIM-1, PIM-2 and PIM-3.				US Patent US8481586 (2013) BindingDB Entry DOI: 10.7270/Q2ZC81GT
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50299245 (7-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carb...) Show SMILES Brc1ccc2[nH]c3c(ccc4c(C=O)c[nH]c34)c2c1 Show InChI InChI=1S/C15H9BrN2O/c16-9-1-4-13-12(5-9)11-3-2-10-8(7-19)6-17-14(10)15(11)18-13/h1-7,17-18H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II US Patent					Assay Description Inhibition assay using PIM-1, PIM-2 and PIM-3.				US Patent US8481586 (2013) BindingDB Entry DOI: 10.7270/Q2ZC81GT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Rattus norvegicus (rat))	BDBM50295874 (4-(1H-indol-3-yl)-5-(4-(trifluoromethyl)phenyl)pyr...) Show SMILES Nc1ncc(-c2ccc(cc2)C(F)(F)F)c(n1)-c1c[nH]c2ccccc12 Show InChI InChI=1S/C19H13F3N4/c20-19(21,22)12-7-5-11(6-8-12)14-9-25-18(23)26-17(14)15-10-24-16-4-2-1-3-13(15)16/h1-10,24H,(H2,23,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of rat recombinant Erk2				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50295873 (4-[2-Amino-4-(1H-indol-3-yl)pyrimidin-5-yl]benzami...) Show SMILES NC(=O)c1ccc(cc1)-c1cnc(N)nc1-c1c[nH]c2ccccc12 Show InChI InChI=1S/C19H15N5O/c20-18(25)12-7-5-11(6-8-12)14-9-23-19(21)24-17(14)15-10-22-16-4-2-1-3-13(15)16/h1-10,22H,(H2,20,25)(H2,21,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A expressed in Escherichia coli				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50295875 (4-(1H-Indol-3-yl)-5-(3-methoxyphenyl)pyrimidin-2-a...) Show SMILES COc1cccc(c1)-c1cnc(N)nc1-c1c[nH]c2ccccc12 Show InChI InChI=1S/C19H16N4O/c1-24-13-6-4-5-12(9-13)15-10-22-19(20)23-18(15)16-11-21-17-8-3-2-7-14(16)17/h2-11,21H,1H3,(H2,20,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A expressed in Escherichia coli				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50295876 (4-(1H-Indol-3-yl)-5-(3-aminophenyl)pyrimidin-2-ami...) Show SMILES Nc1cccc(c1)-c1cnc(N)nc1-c1c[nH]c2ccccc12 Show InChI InChI=1S/C18H15N5/c19-12-5-3-4-11(8-12)14-9-22-18(20)23-17(14)15-10-21-16-7-2-1-6-13(15)16/h1-10,21H,19H2,(H2,20,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A expressed in Escherichia coli				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50299250 (7-(2,4-Difluorophenyl)-1,10-dihydropyrrolo[2,3-a]c...) Show SMILES Fc1ccc(c(F)c1)-c1ccc2[nH]c3c(ccc4c(C=O)c[nH]c34)c2c1 Show InChI InChI=1S/C21H12F2N2O/c22-13-2-3-14(18(23)8-13)11-1-6-19-17(7-11)16-5-4-15-12(10-26)9-24-20(15)21(16)25-19/h1-10,24-25H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	US Patent	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II US Patent					Assay Description Inhibition assay using PIM-1, PIM-2 and PIM-3.				US Patent US8481586 (2013) BindingDB Entry DOI: 10.7270/Q2ZC81GT
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50299248 (1,10-Dihydropyrrolo[2,3-a]carbazole-3-carboxamide ...) Show SMILES NC(=O)c1c[nH]c2c1ccc1c3ccccc3[nH]c21 Show InChI InChI=1S/C15H11N3O/c16-15(19)11-7-17-13-10(11)6-5-9-8-3-1-2-4-12(8)18-14(9)13/h1-7,17-18H,(H2,16,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	US Patent	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II US Patent					Assay Description Inhibition assay using PIM-1, PIM-2 and PIM-3.				US Patent US8481586 (2013) BindingDB Entry DOI: 10.7270/Q2ZC81GT
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50295877 (4-[2-Amino-4-(1-methyl-1H-indol-3-yl)pyrimidin-5-y...) Show SMILES Cn1cc(-c2nc(N)ncc2-c2ccc(cc2)C(O)=O)c2ccccc12 Show InChI InChI=1S/C20H16N4O2/c1-24-11-16(14-4-2-3-5-17(14)24)18-15(10-22-20(21)23-18)12-6-8-13(9-7-12)19(25)26/h2-11H,1H3,(H,25,26)(H2,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A expressed in Escherichia coli				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Rattus norvegicus (rat))	BDBM50295878 (4-(1-Methyl-1H-indol-3-yl)-5-(pyridin-4-yl)pyrimid...) Show SMILES Cn1cc(-c2nc(N)ncc2-c2ccncc2)c2ccccc12 Show InChI InChI=1S/C18H15N5/c1-23-11-15(13-4-2-3-5-16(13)23)17-14(10-21-18(19)22-17)12-6-8-20-9-7-12/h2-11H,1H3,(H2,19,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of rat recombinant Erk2				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50295879 (4-(1-Methyl-1H-indol-3-yl)-5-(3-aminophenyl)pyrimi...) Show SMILES Cn1cc(-c2nc(N)ncc2-c2cccc(N)c2)c2ccccc12 Show InChI InChI=1S/C19H17N5/c1-24-11-16(14-7-2-3-8-17(14)24)18-15(10-22-19(21)23-18)12-5-4-6-13(20)9-12/h2-11H,20H2,1H3,(H2,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A expressed in Escherichia coli				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Rattus norvegicus (rat))	BDBM50295873 (4-[2-Amino-4-(1H-indol-3-yl)pyrimidin-5-yl]benzami...) Show SMILES NC(=O)c1ccc(cc1)-c1cnc(N)nc1-c1c[nH]c2ccccc12 Show InChI InChI=1S/C19H15N5O/c20-18(25)12-7-5-11(6-8-12)14-9-23-19(21)24-17(14)15-10-22-16-4-2-1-3-13(15)16/h1-10,22H,(H2,20,25)(H2,21,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of rat recombinant Erk2				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50295880 (4-[2-Amino-4-(1-methyl-1H-indol-3-yl)pyrimidin-5-y...) Show SMILES Cn1cc(-c2nc(N)ncc2-c2ccc(cc2)C(N)=O)c2ccccc12 Show InChI InChI=1S/C20H17N5O/c1-25-11-16(14-4-2-3-5-17(14)25)18-15(10-23-20(22)24-18)12-6-8-13(9-7-12)19(21)26/h2-11H,1H3,(H2,21,26)(H2,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A expressed in Escherichia coli				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50295874 (4-(1H-indol-3-yl)-5-(4-(trifluoromethyl)phenyl)pyr...) Show SMILES Nc1ncc(-c2ccc(cc2)C(F)(F)F)c(n1)-c1c[nH]c2ccccc12 Show InChI InChI=1S/C19H13F3N4/c20-19(21,22)12-7-5-11(6-8-12)14-9-25-18(23)26-17(14)15-10-24-16-4-2-1-3-13(15)16/h1-10,24H,(H2,23,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A expressed in Escherichia coli				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50295878 (4-(1-Methyl-1H-indol-3-yl)-5-(pyridin-4-yl)pyrimid...) Show SMILES Cn1cc(-c2nc(N)ncc2-c2ccncc2)c2ccccc12 Show InChI InChI=1S/C18H15N5/c1-23-11-15(13-4-2-3-5-16(13)23)17-14(10-21-18(19)22-17)12-6-8-20-9-7-12/h2-11H,1H3,(H2,19,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A expressed in Escherichia coli				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50295872 (5-Iodo-4-(1-Methyl-1H-indol-3-yl)pyrimidin-2-amine...) Show SMILES Cn1cc(-c2nc(N)ncc2I)c2ccccc12 Show InChI InChI=1S/C13H11IN4/c1-18-7-9(8-4-2-3-5-11(8)18)12-10(14)6-16-13(15)17-12/h2-7H,1H3,(H2,15,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50295881 (4-(1H-indol-3-yl)-5-(4-(trifluoromethoxy)phenyl)py...) Show SMILES Nc1ncc(-c2ccc(OC(F)(F)F)cc2)c(n1)-c1c[nH]c2ccccc12 Show InChI InChI=1S/C19H13F3N4O/c20-19(21,22)27-12-7-5-11(6-8-12)14-9-25-18(23)26-17(14)15-10-24-16-4-2-1-3-13(15)16/h1-10,24H,(H2,23,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A expressed in Escherichia coli				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50295882 (4-(1-Methyl-1H-indol-3-yl)-5-(3-methoxyphenyl)pyri...) Show SMILES COc1cccc(c1)-c1cnc(N)nc1-c1cn(C)c2ccccc12 Show InChI InChI=1S/C20H18N4O/c1-24-12-17(15-8-3-4-9-18(15)24)19-16(11-22-20(21)23-19)13-6-5-7-14(10-13)25-2/h3-12H,1-2H3,(H2,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A expressed in Escherichia coli				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Rattus norvegicus (rat))	BDBM50295875 (4-(1H-Indol-3-yl)-5-(3-methoxyphenyl)pyrimidin-2-a...) Show SMILES COc1cccc(c1)-c1cnc(N)nc1-c1c[nH]c2ccccc12 Show InChI InChI=1S/C19H16N4O/c1-24-13-6-4-5-12(9-13)15-10-22-19(20)23-18(15)16-11-21-17-8-3-2-7-14(16)17/h2-11,21H,1H3,(H2,20,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of rat recombinant Erk2				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50295883 (4-(1-Methyl-1H-indol-3-yl)-5,50-bipyrimidin-2-amin...) Show SMILES Cn1cc(-c2nc(N)ncc2-c2cncnc2)c2ccccc12 Show InChI InChI=1S/C17H14N6/c1-23-9-14(12-4-2-3-5-15(12)23)16-13(8-21-17(18)22-16)11-6-19-10-20-7-11/h2-10H,1H3,(H2,18,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A expressed in Escherichia coli				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Rattus norvegicus (rat))	BDBM50295881 (4-(1H-indol-3-yl)-5-(4-(trifluoromethoxy)phenyl)py...) Show SMILES Nc1ncc(-c2ccc(OC(F)(F)F)cc2)c(n1)-c1c[nH]c2ccccc12 Show InChI InChI=1S/C19H13F3N4O/c20-19(21,22)27-12-7-5-11(6-8-12)14-9-25-18(23)26-17(14)15-10-24-16-4-2-1-3-13(15)16/h1-10,24H,(H2,23,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of rat recombinant Erk2				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Rattus norvegicus (rat))	BDBM50295872 (5-Iodo-4-(1-Methyl-1H-indol-3-yl)pyrimidin-2-amine...) Show SMILES Cn1cc(-c2nc(N)ncc2I)c2ccccc12 Show InChI InChI=1S/C13H11IN4/c1-18-7-9(8-4-2-3-5-11(8)18)12-10(14)6-16-13(15)17-12/h2-7H,1H3,(H2,15,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of rat recombinant Erk2				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50295884 (1-(4-(2-amino-4-(1-methyl-1H-indol-3-yl)pyrimidin-...) Show SMILES CC(=O)c1ccc(cc1)-c1cnc(N)nc1-c1cn(C)c2ccccc12 Show InChI InChI=1S/C21H18N4O/c1-13(26)14-7-9-15(10-8-14)17-11-23-21(22)24-20(17)18-12-25(2)19-6-4-3-5-16(18)19/h3-12H,1-2H3,(H2,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A expressed in Escherichia coli				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50295878 (4-(1-Methyl-1H-indol-3-yl)-5-(pyridin-4-yl)pyrimid...) Show SMILES Cn1cc(-c2nc(N)ncc2-c2ccncc2)c2ccccc12 Show InChI InChI=1S/C18H15N5/c1-23-11-15(13-4-2-3-5-16(13)23)17-14(10-21-18(19)22-17)12-6-8-20-9-7-12/h2-11H,1H3,(H2,19,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Rattus norvegicus (rat))	BDBM50295876 (4-(1H-Indol-3-yl)-5-(3-aminophenyl)pyrimidin-2-ami...) Show SMILES Nc1cccc(c1)-c1cnc(N)nc1-c1c[nH]c2ccccc12 Show InChI InChI=1S/C18H15N5/c19-12-5-3-4-11(8-12)14-9-22-18(20)23-17(14)15-10-21-16-7-2-1-6-13(15)16/h1-10,21H,19H2,(H2,20,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of rat recombinant Erk2				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Rattus norvegicus (rat))	BDBM50295880 (4-[2-Amino-4-(1-methyl-1H-indol-3-yl)pyrimidin-5-y...) Show SMILES Cn1cc(-c2nc(N)ncc2-c2ccc(cc2)C(N)=O)c2ccccc12 Show InChI InChI=1S/C20H17N5O/c1-25-11-16(14-4-2-3-5-17(14)25)18-15(10-23-20(22)24-18)12-6-8-13(9-7-12)19(21)26/h2-11H,1H3,(H2,21,26)(H2,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of rat recombinant Erk2				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50295882 (4-(1-Methyl-1H-indol-3-yl)-5-(3-methoxyphenyl)pyri...) Show SMILES COc1cccc(c1)-c1cnc(N)nc1-c1cn(C)c2ccccc12 Show InChI InChI=1S/C20H18N4O/c1-24-12-17(15-8-3-4-9-18(15)24)19-16(11-22-20(21)23-19)13-6-5-7-14(10-13)25-2/h3-12H,1-2H3,(H2,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50295881 (4-(1H-indol-3-yl)-5-(4-(trifluoromethoxy)phenyl)py...) Show SMILES Nc1ncc(-c2ccc(OC(F)(F)F)cc2)c(n1)-c1c[nH]c2ccccc12 Show InChI InChI=1S/C19H13F3N4O/c20-19(21,22)27-12-7-5-11(6-8-12)14-9-25-18(23)26-17(14)15-10-24-16-4-2-1-3-13(15)16/h1-10,24H,(H2,23,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50295884 (1-(4-(2-amino-4-(1-methyl-1H-indol-3-yl)pyrimidin-...) Show SMILES CC(=O)c1ccc(cc1)-c1cnc(N)nc1-c1cn(C)c2ccccc12 Show InChI InChI=1S/C21H18N4O/c1-13(26)14-7-9-15(10-8-14)17-11-23-21(22)24-20(17)18-12-25(2)19-6-4-3-5-16(18)19/h3-12H,1-2H3,(H2,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50295885 (5-(biphenyl-4-yl)-4-(1-methyl-1H-indol-3-yl)pyrimi...) Show SMILES Cn1cc(-c2nc(N)ncc2-c2ccc(cc2)-c2ccccc2)c2ccccc12 Show InChI InChI=1S/C25H20N4/c1-29-16-22(20-9-5-6-10-23(20)29)24-21(15-27-25(26)28-24)19-13-11-18(12-14-19)17-7-3-2-4-8-17/h2-16H,1H3,(H2,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50295875 (4-(1H-Indol-3-yl)-5-(3-methoxyphenyl)pyrimidin-2-a...) Show SMILES COc1cccc(c1)-c1cnc(N)nc1-c1c[nH]c2ccccc12 Show InChI InChI=1S/C19H16N4O/c1-24-13-6-4-5-12(9-13)15-10-22-19(20)23-18(15)16-11-21-17-8-3-2-7-14(16)17/h2-11,21H,1H3,(H2,20,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Rattus norvegicus (rat))	BDBM50295883 (4-(1-Methyl-1H-indol-3-yl)-5,50-bipyrimidin-2-amin...) Show SMILES Cn1cc(-c2nc(N)ncc2-c2cncnc2)c2ccccc12 Show InChI InChI=1S/C17H14N6/c1-23-9-14(12-4-2-3-5-15(12)23)16-13(8-21-17(18)22-16)11-6-19-10-20-7-11/h2-10H,1H3,(H2,18,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of rat recombinant Erk2				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50295876 (4-(1H-Indol-3-yl)-5-(3-aminophenyl)pyrimidin-2-ami...) Show SMILES Nc1cccc(c1)-c1cnc(N)nc1-c1c[nH]c2ccccc12 Show InChI InChI=1S/C18H15N5/c19-12-5-3-4-11(8-12)14-9-22-18(20)23-17(14)15-10-21-16-7-2-1-6-13(15)16/h1-10,21H,19H2,(H2,20,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50295879 (4-(1-Methyl-1H-indol-3-yl)-5-(3-aminophenyl)pyrimi...) Show SMILES Cn1cc(-c2nc(N)ncc2-c2cccc(N)c2)c2ccccc12 Show InChI InChI=1S/C19H17N5/c1-24-11-16(14-7-2-3-8-17(14)24)18-15(10-22-19(21)23-18)12-5-4-6-13(20)9-12/h2-11H,20H2,1H3,(H2,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50295873 (4-[2-Amino-4-(1H-indol-3-yl)pyrimidin-5-yl]benzami...) Show SMILES NC(=O)c1ccc(cc1)-c1cnc(N)nc1-c1c[nH]c2ccccc12 Show InChI InChI=1S/C19H15N5O/c20-18(25)12-7-5-11(6-8-12)14-9-23-19(21)24-17(14)15-10-22-16-4-2-1-3-13(15)16/h1-10,22H,(H2,20,25)(H2,21,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50295880 (4-[2-Amino-4-(1-methyl-1H-indol-3-yl)pyrimidin-5-y...) Show SMILES Cn1cc(-c2nc(N)ncc2-c2ccc(cc2)C(N)=O)c2ccccc12 Show InChI InChI=1S/C20H17N5O/c1-25-11-16(14-4-2-3-5-17(14)25)18-15(10-23-20(22)24-18)12-6-8-13(9-7-12)19(21)26/h2-11H,1H3,(H2,21,26)(H2,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50295877 (4-[2-Amino-4-(1-methyl-1H-indol-3-yl)pyrimidin-5-y...) Show SMILES Cn1cc(-c2nc(N)ncc2-c2ccc(cc2)C(O)=O)c2ccccc12 Show InChI InChI=1S/C20H16N4O2/c1-24-11-16(14-4-2-3-5-17(14)24)18-15(10-22-20(21)23-18)12-6-8-13(9-7-12)19(25)26/h2-11H,1H3,(H,25,26)(H2,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50295883 (4-(1-Methyl-1H-indol-3-yl)-5,50-bipyrimidin-2-amin...) Show SMILES Cn1cc(-c2nc(N)ncc2-c2cncnc2)c2ccccc12 Show InChI InChI=1S/C17H14N6/c1-23-9-14(12-4-2-3-5-15(12)23)16-13(8-21-17(18)22-16)11-6-19-10-20-7-11/h2-10H,1H3,(H2,18,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50295885 (5-(biphenyl-4-yl)-4-(1-methyl-1H-indol-3-yl)pyrimi...) Show SMILES Cn1cc(-c2nc(N)ncc2-c2ccc(cc2)-c2ccccc2)c2ccccc12 Show InChI InChI=1S/C25H20N4/c1-29-16-22(20-9-5-6-10-23(20)29)24-21(15-27-25(26)28-24)19-13-11-18(12-14-19)17-7-3-2-4-8-17/h2-16H,1H3,(H2,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A expressed in Escherichia coli				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Rattus norvegicus (rat))	BDBM50295884 (1-(4-(2-amino-4-(1-methyl-1H-indol-3-yl)pyrimidin-...) Show SMILES CC(=O)c1ccc(cc1)-c1cnc(N)nc1-c1cn(C)c2ccccc12 Show InChI InChI=1S/C21H18N4O/c1-13(26)14-7-9-15(10-8-14)17-11-23-21(22)24-20(17)18-12-25(2)19-6-4-3-5-16(18)19/h3-12H,1-2H3,(H2,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of rat recombinant Erk2				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Rattus norvegicus (rat))	BDBM50295885 (5-(biphenyl-4-yl)-4-(1-methyl-1H-indol-3-yl)pyrimi...) Show SMILES Cn1cc(-c2nc(N)ncc2-c2ccc(cc2)-c2ccccc2)c2ccccc12 Show InChI InChI=1S/C25H20N4/c1-29-16-22(20-9-5-6-10-23(20)29)24-21(15-27-25(26)28-24)19-13-11-18(12-14-19)17-7-3-2-4-8-17/h2-16H,1H3,(H2,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of rat recombinant Erk2				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Rattus norvegicus (rat))	BDBM50295882 (4-(1-Methyl-1H-indol-3-yl)-5-(3-methoxyphenyl)pyri...) Show SMILES COc1cccc(c1)-c1cnc(N)nc1-c1cn(C)c2ccccc12 Show InChI InChI=1S/C20H18N4O/c1-24-12-17(15-8-3-4-9-18(15)24)19-16(11-22-20(21)23-19)13-6-5-7-14(10-13)25-2/h3-12H,1-2H3,(H2,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of rat recombinant Erk2				Bioorg Med Chem 17: 4420-4 (2009) Article DOI: 10.1016/j.bmc.2009.05.017 BindingDB Entry DOI: 10.7270/Q2639PSH
					More data for this Ligand-Target Pair

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