| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Serine/threonine-protein kinase pim-3 |
|---|
| Ligand | BDBM104139 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | PIM-3 Enzyme Assay |
|---|
| pH | 7.4±0 |
|---|
| Temperature | 295.15±0 K |
|---|
| IC50 | 4±0.0 nM |
|---|
| Citation |  Allen, S; Celeste, LL; Davis, TG; DeLisle, RK; Greschuk, JM; Gross, SD; Hicken, EJ; Jackson, LJ; Kallan, NC; Lyssikatos, JP; Marmsater, FP; Munson, MC; Pheneger, J; Rast, B; Robinson, JE; Schlachter, ST; Topalov, GT; Wright, AD; Zhao, Q Triazolopyridine compounds as PIM kinase inhibitors US Patent US8575145 Publication Date 11/5/2013 |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Serine/threonine-protein kinase pim-3 |
|---|
| Name: | Serine/threonine-protein kinase pim-3 |
|---|
| Synonyms: | Kid1 | PIM3_RAT | Pim3 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 35997.25 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | O70444 |
|---|
| Residue: | 326 |
|---|
| Sequence: | MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKVYQVGAVLGSGGFGTVYAGSRI
ADGLPVAVKHVVKERVTEWGSLGGMAVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFL
LVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHNCGVVHRDIKDENLLVDL
RSGELKLIDFGSGAVLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVC
GDIPFEQDEEILRGRLFFRRRVSPECQQLIEWCLSLRPSERPSLDQIAAHPWMLGTEGSV
PENCDLRLCALDTDDGASTTSSSESL
|
|
|
|---|
| BDBM104139 |
|---|
| n/a |
|---|
| Name | BDBM104139 |
|---|
| Synonyms: | US8575145, 16 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H21N5O |
|---|
| Mol. Mass. | 359.4243 |
|---|
| SMILES | C(Oc1cccc2ccc(nc12)-c1nnc2ccccn12)C1CCCNC1 |
|---|
| Structure | 
|
|---|
Search and Browse
