| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Prolyl hydroxylase EGLN3 |
|---|
| Ligand | BDBM107701 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Enzyme Assay |
|---|
| IC50 | 3.75e+4±n/a nM |
|---|
| Citation |  Kawamoto, RM; Wu, S; Warshakoon, NC; Evdokimov, AG; Greis, KD; Boyer, AS Prolyl hydroxylase inhibitors and methods of use US Patent US8598210 Publication Date 12/3/2013 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Prolyl hydroxylase EGLN3 |
|---|
| Name: | Prolyl hydroxylase EGLN3 |
|---|
| Synonyms: | EGLN3 | EGLN3_HUMAN | Egl nine homolog 3 (EGLIN3) | Egl nine homolog 3 (EGLN3) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 27265.54 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q9H6Z9 |
|---|
| Residue: | 239 |
|---|
| Sequence: | MPLGHIMRLDLEKIALEYIVPCLHEVGFCYLDNFLGEVVGDCVLERVKQLHCTGALRDGQ
LAGPRAGVSKRHLRGDQITWIGGNEEGCEAISFLLSLIDRLVLYCGSRLGKYYVKERSKA
MVACYPGNGTGYVRHVDNPNGDGRCITCIYYLNKNWDAKLHGGILRIFPEGKSFIADVEP
IFDRLLFFWSDRRNPHEVQPSYATRYAMTVWYFDAEERAEAKKKFRNLTRKTESALTED
|
|
|
|---|
| BDBM107701 |
|---|
| n/a |
|---|
| Name | BDBM107701 |
|---|
| Synonyms: | US11426393, Compound Table XV.7 | US8598210, Table XV, 7 | US8722895, 7: {[5-(2-Chloro-phenyl)-3-hydroxy-pyridine- 2-carbonyl]-amino}-acetic acid methyl ester | US9598370, Example 00132 | USRE47437, Example {[5-(2-Chloro-phenyl)-3-hydroxy-pyridine-2-carbonyl]-amino}-acetic acid methyl ester |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H13ClN2O4 |
|---|
| Mol. Mass. | 320.728 |
|---|
| SMILES | COC(=O)CNC(=O)c1ncc(cc1O)-c1ccccc1Cl |
|---|
| Structure | 
|
|---|
Search and Browse
