| Reaction Details |
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 | Report a problem with these data |
| Target | Orexin receptor type 2 |
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| Ligand | BDBM119654 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radioligand Binding |
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| Temperature | 277.15±n/a K |
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| Ki | 20±n/a nM |
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| Comments | extracted |
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| Citation |  Branstetter, BJ; Letavic, MA; Ly, KS; Rudolph, DA; Savall, BM; Shah, CR; Shireman, BT Fused heterocyclic compounds as orexin receptor modulators US Patent US8680275 Publication Date 3/25/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| Orexin receptor type 2 |
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| Name: | Orexin receptor type 2 |
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| Synonyms: | HCRTR2 | Hypocretin receptor type 2 | OX2R_HUMAN | Orexin receptor type 2 (OR 2) | Orexin receptor type 2 (OR-2) | Orexin receptor type 2 (OX2) | Orexin receptor type 2 (OX2R) | Orexin receptor type 2 (OxR2) | Ox-2-R | Ox2-R |
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| Type: | Protein |
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| Mol. Mass.: | 50710.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O43614 |
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| Residue: | 444 |
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| Sequence: | MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV
LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARR
KTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAAN
PIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFDNISKL
SEQVVLTSISTLPAANGAGPLQNW
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| BDBM119654 |
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| n/a |
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| Name | BDBM119654 |
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| Synonyms: | US8680275, 23 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H23FN6O |
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| Mol. Mass. | 418.4667 |
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| SMILES | Cc1cc(C)nc(n1)N1CC2CCN(CC12)C(=O)c1cc(F)ccc1-c1ncccn1 |
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| Structure | 
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