| Reaction Details |
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 | Report a problem with these data |
| Target | Integrin-linked protein kinase |
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| Ligand | BDBM123933 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro Ezyme Assay |
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| Temperature | 313.15±n/a K |
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| IC50 | 40±n/a nM |
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| Comments | extracted |
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| Citation |  Zhang, Z; Daynard, TS; Wang, S; Du, X; Chopiuk, GB; Yan, J; Chen, J; Sviridov, SV Pyrazolylbenzothiazole derivatives and their use as therapeutic agents US Patent US8754233 Publication Date 6/17/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Integrin-linked protein kinase |
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| Name: | Integrin-linked protein kinase |
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| Synonyms: | ILK | ILK1 | ILK2 | ILK_HUMAN | Integrin-linked protein kinase (ILK) | Serine/threonine-protein kinase ILK-1 |
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| Type: | Protein |
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| Mol. Mass.: | 51429.75 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13418 |
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| Residue: | 452 |
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| Sequence: | MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARI
NVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLV
ANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNG
TLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECP
RLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALD
MARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEA
LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPH
VCKLMKICMNEDPAKRPKFDMIVPILEKMQDK
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|
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| BDBM123933 |
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| n/a |
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| Name | BDBM123933 |
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| Synonyms: | US8754233, 2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-5-fluoro-benzothiazole-6-sulfonic acid methylamide |
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| Type | Small organic molecule |
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| Emp. Form. | C12H12FN5O2S2 |
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| Mol. Mass. | 341.384 |
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| SMILES | CNS(=O)(=O)c1cc2sc(nc2cc1F)-c1c(C)[nH]nc1N |
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| Structure | 
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