| Reaction Details |
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 | Report a problem with these data |
| Target | Neuraminidase |
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| Ligand | BDBM4734 |
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| Substrate/Competitor | BDBM4702 |
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| Meas. Tech. | Neuraminidase Inhibition Assay |
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| pH | 6.5±n/a |
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| Temperature | 310.15±n/a K |
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| IC50 | 6000±n/a nM |
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| Citation |  Chand, P; Kotian, PL; Morris, PE; Bantia, S; Walsh, DA; Babu, YS Synthesis and inhibitory activity of benzoic acid and pyridine derivatives on influenza neuraminidase. Bioorg Med Chem13:2665-78 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Neuraminidase |
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| Name: | Neuraminidase |
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| Synonyms: | Influenza A Virus Neuraminidase | NA | NRAM_I75A5 | Neuraminidase A |
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| Type: | Enzyme |
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| Mol. Mass.: | 52468.81 |
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| Organism: | Influenza A virus (N9) |
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| Description: | P03472 |
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| Residue: | 470 |
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| Sequence: | MNPNQKILCTSATALVIGTIAVLIGITNLGLNIGLHLKPSCNCSHSQPEATNASQTIINN
YYNDTNITQISNTNIQVEERAIRDFNNLTKGLCTINSWHIYGKDNAVRIGEDSDVLVTRE
PYVSCDPDECRFYALSQGTTIRGKHSNGTIHDRSQYRALISWPLSSPPTVYNSRVECIGW
SSTSCHDGKTRMSICISGPNNNASAVIWYNRRPVTEINTWARNILRTQESECVCHNGVCP
VVFTDGSATGPAETRIYYFKEGKILKWEPLAGTAKHIEECSCYGERAEITCTCRDNWQGS
NRPVIRIDPVAMTHTSQYICSPVLTDNPRPNDPTVGKCNDPYPGNNNNGVKGFSYLDGVN
TWLGRTISIASRSGYEMLKVPNALTDDKSKPTQGQTIVLNTDWSGYSGSFMDYWAEGECY
RACFYVELIRGRPKEDKVWWTSNSIVSMCSSTEFLGQWDWPDGAKIEYFL
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| BDBM4734 |
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| BDBM4702 |
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| Name | BDBM4734 |
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| Synonyms: | 5-Acetylamino-6-[(aminoiminomethyl)amino]pyridine-2-carboxylic acid | 6-carbamimidamido-5-acetamidopyridine-2-carboxylic acid | pyridine deriv. 35 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H11N5O3 |
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| Mol. Mass. | 237.2153 |
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| SMILES | CC(=O)Nc1ccc(nc1N=C(N)N)C(O)=O |w:10.10| |
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| Structure | 
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