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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fatty acid synthase | ||
| Ligand | BDBM128362 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Biological Assay | ||
| pH | 7±n/a | ||
| IC50 | 5±n/a nM | ||
| Comments | extracted | ||
| Citation |  Adams, ND; Aquino, CJ; Chaudhari, AM; Ghergurovich, JM; Kiesow, TJ; Parrish, CA; Reif, AJ; Wiggall, K Triazolones as fatty acid synthase inhibitors US Patent US8802864 Publication Date 8/12/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fatty acid synthase | |||
| Name: | Fatty acid synthase | ||
| Synonyms: | FAS | FASN | FAS_HUMAN | Fatty acid synthase (FASN) | HU FASN | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 273419.37 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P49327 | ||
| Residue: | 2511 | ||
| Sequence: |
| ||
| BDBM128362 | |||
| n/a | |||
| Name | BDBM128362 | ||
| Synonyms: | US8802864, 42 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C26H27N5O2 | ||
| Mol. Mass. | 441.5249 | ||
| SMILES | Cc1cc(ccc1-n1c(C[C@@H]2CCN(C2)C(=O)C2CC2)n[nH]c1=O)-c1ccc2cc[nH]c2c1 |r,wU:10.10,(-2.73,-4.92,;-1.96,-3.59,;-.42,-3.59,;.35,-2.25,;-.42,-.92,;-1.96,-.92,;-2.73,-2.25,;-4.27,-2.25,;-5.17,-1.01,;-4.78,.48,;-3.29,.88,;-2.04,-.03,;-.8,.88,;-1.27,2.34,;-2.81,2.34,;-.18,3.43,;-.58,4.92,;1.3,3.03,;2.39,1.95,;2.79,3.43,;-6.64,-1.48,;-6.64,-3.02,;-5.17,-3.5,;-4.4,-4.83,;1.89,-2.25,;2.66,-3.59,;4.2,-3.59,;4.97,-2.25,;6.48,-1.93,;6.64,-.4,;5.23,.23,;4.2,-.92,;2.66,-.92,)| | ||
| Structure | 
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