| Reaction Details |
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 | Report a problem with these data |
| Target | Transitional endoplasmic reticulum ATPase |
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| Ligand | BDBM163097 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ADP Glo Assay |
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| pH | 7.5±n/a |
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| Temperature | 310.15±n/a K |
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| IC50 | <2000±n/a nM |
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| Comments | extracted |
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| Citation |  Zhou, H; Parlati, F; Wustrow, D Fused pyrimidines and substituted quinazolines as inhibitors of p97 US Patent US9062026 Publication Date 6/23/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Transitional endoplasmic reticulum ATPase |
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| Name: | Transitional endoplasmic reticulum ATPase |
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| Synonyms: | TERA_HUMAN | Transitional endoplasmic reticulum ATPase | VCP | Valosin containing protein, p97 subunit | Valosin-containing protein |
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| Type: | Enzyme |
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| Mol. Mass.: | 89300.63 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P55072 |
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| Residue: | 806 |
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| Sequence: | MASGADSKGDDLSTAILKQKNRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLK
GKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPID
DTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDT
VIHCEGEPIKREDEEESLNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRG
ILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAI
IFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRF
GRFDREVDIGIPDATGRLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAAL
QAIRKKMDLIDLEDETIDAEVMNSLAVTMDDFRWALSQSNPSALRETVVEVPQVTWEDIG
GLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFI
SIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKARGGNIGDGGGAADRV
INQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRVAILKAN
LRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRACKLAIRESIESEIRRERERQTNPSAM
EVEEDDPVPEIRRDHFEEAMRFARRSVSDNDIRKYEMFAQTLQQSRGFGSFRFPSGNQGG
AGPSQGSGGGTGGSVYTEDNDDDLYG
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| BDBM163097 |
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| n/a |
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| Name | BDBM163097 |
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| Synonyms: | US9062026, Table III, Compound 25 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H22N6O |
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| Mol. Mass. | 410.4711 |
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| SMILES | CNc1nc2ccccc2n1-c1nc(NCc2ccccc2)c2cccc(OC)c2n1 |
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| Structure | 
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