| Reaction Details |
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 | Report a problem with these data |
| Target | Signal transducer and activator of transcription 5A |
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| Ligand | BDBM165192 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence Polarization Assay |
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| Ki | 1.3e+4±7e+2 nM |
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| IC50 | 26400±1400 nM |
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| Citation |  Elumalai, N; Berg, A; Rubner, S; Berg, T Phosphorylation of Capsaicinoid Derivatives Provides Highly Potent and Selective Inhibitors of the Transcription Factor STAT5b. ACS Chem Biol10:2884-90 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Signal transducer and activator of transcription 5A |
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| Name: | Signal transducer and activator of transcription 5A |
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| Synonyms: | STA5A_HUMAN | STAT5 | STAT5A | Signal transducer and activator of transcription 5A | Transcription factor STAT5a (STAT5a) |
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| Type: | Protein |
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| Mol. Mass.: | 90643.89 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 794 |
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| Sequence: | MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQL
LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQKTYDRCPLELVRCIRHILYNEQRLV
REANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQAQFAQLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLL
RKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLC
QQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKL
NVHMNPPQVKATIISEQQAKSLLKNENTRNECSGEILNNCCVMEYHQATGTLSAHFRNMS
LKRIKRADRRGAESVTEEKFTVLFESQFSVGSNELVFQVKTLSLPVVVIVHGSQDHNATA
TVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNN
SSSHLEDYSGLSVSWSQFNRENLPGWNYTFWQWFDGVMEVLKKHHKPHWNDGAILGFVNK
QQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSPERNLWNLKPFTTRDFSIRSLADRL
GDLSYLIYVFPDRPKDEVFSKYYTPVLAKAVDGYVKPQIKQVVPEFVNASADAGGSSATY
MDQAPSPAVCPQAPYNMYPQNPDHVLDQDGEFDLDETMDVARHVEELLRRPMDSLDSRLS
PPAGLFTSARGSLS
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| BDBM165192 |
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| n/a |
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| Name | BDBM165192 |
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| Synonyms: | 4-((8-Methylnonanamido)methyl)-1,2-phenylene bis(dihydrogen phosphate) (6a) |
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| Type | n/a |
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| Emp. Form. | C17H29NO9P2 |
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| Mol. Mass. | 453.361 |
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| SMILES | CC(C)CCCCCCC(=O)NCc1ccc(OP(O)(O)=O)c(OP(O)(O)=O)c1 |
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| Structure | 
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