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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Dipeptidyl peptidase 4 [K6R,T557I] | ||
| Ligand | BDBM167936 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | DPP-IV Inhibition Activity | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 73±0.0 nM | ||
| Comments | extracted | ||
| Citation |  Gomha, SM; Eldebss, TM; Badrey, MG; Abdulla, MM; Mayhoub, AS Novel 4-heteroaryl-antipyrines as DPP-IV inhibitors. Chem Biol Drug Des86:1292-303 (2015) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Dipeptidyl peptidase 4 [K6R,T557I] | |||
| Name: | Dipeptidyl peptidase 4 [K6R,T557I] | ||
| Synonyms: | ADCP2 | CD26 | DPP4 | DPP4_HUMAN | Dipeptidyl peptidase IV (DPP-IV) | Dipeptidyl peptidase-IV (DDP-4) | Dipeptidyl peptidase-IV (DPP-IV) | ||
| Type: | Protein | ||
| Mol. Mass.: | 88325.11 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P27487[K6R,T557I] | ||
| Residue: | 766 | ||
| Sequence: |
| ||
| BDBM167936 | |||
| n/a | |||
| Name | BDBM167936 | ||
| Synonyms: | 1,5-Dimethyl-2-phenyl-4-(3-(phenylsulfonyl)benzo[4,5]imidazo[1,2-a]pyrimidin-4-yl)-1H-pyrazol-3(2H)-one (14) | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H21N5O3S | ||
| Mol. Mass. | 495.552 | ||
| SMILES | Cc1c(-c2c(cnc3nc4ccccc4n23)S(=O)(=O)c2ccccc2)c(=O)n(-c2ccccc2)n1C |(9.96,8.33,;8.42,8.41,;7.45,7.21,;7.85,5.72,;9.34,5.32,;9.74,3.84,;8.65,2.75,;7.16,3.15,;5.87,2.31,;4.67,3.28,;3.15,3.04,;2.18,4.23,;2.73,5.67,;4.26,5.91,;5.22,4.71,;6.76,4.63,;10.43,6.41,;9.34,7.5,;11.52,5.32,;11.52,7.5,;13,7.1,;14.09,8.19,;13.69,9.68,;12.21,10.08,;11.12,8.99,;6.02,7.76,;4.72,6.92,;6.1,9.3,;4.9,10.27,;5.14,11.79,;3.94,12.76,;2.51,12.21,;2.26,10.69,;3.46,9.72,;7.58,9.7,;8.14,11.14,)| | ||
| Structure | 
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