Reaction Details | |||
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Target | Opioid growth factor receptor-like protein 1 | ||
Ligand | BDBM177924 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Binding Assay | ||
pH | 7.4±n/a | ||
Temperature | 298.15±n/a K | ||
Ki | 3.2±n/a nM | ||
Comments | extracted | ||
Citation | Hinze, C; Aulenbacher, O; Sundermann, B; Oberboersch, S; Friderichs, E; Englberger, W; Koegel, B; Linz, K; Schick, H; Sonnenschein, H; Henkel, B; Rose, VS; Lipkin, MJ Process for preparing spirocyclic cyclohexane compounds, compositions containing such compounds and method of using such compounds US Patent US9120797 Publication Date 9/1/2015 | ||
More Info.: | Get all data from this article, Assay Method | ||
Opioid growth factor receptor-like protein 1 | |||
Name: | Opioid growth factor receptor-like protein 1 | ||
Synonyms: | OGFRL1 | OGRL1_HUMAN | Opioid Receptor-Like Receptor (ORL-1) | Opioid growth factor receptor-like protein 1 (ORL-1) | Opioid growth factor receptor-like protein 1 (ORL1) | Opioid receptor-like (ORL-1) | Opioid receptor-like (ORL1) | Opioid receptor-like protein 1 (OGL1) | Opioid receptor-like receptor (ORL1) | ||
Type: | Protein | ||
Mol. Mass.: | 51247.53 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q5TC84 | ||
Residue: | 451 | ||
Sequence: |
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BDBM177924 | |||
n/a | |||
Name | BDBM177924 | ||
Synonyms: | US9120797, 22 | ||
Type | Small organic molecule | ||
Emp. Form. | C24H27FN2O | ||
Mol. Mass. | 378.4824 | ||
SMILES | CN(C)C1(CCC2(CC1)OCCc1c2[nH]c2ccccc12)c1ccc(F)cc1 |(4.75,.43,;3.27,.83,;2.87,2.31,;2.18,-.26,;1.41,-1.6,;-.13,-1.6,;-.9,-.26,;-.13,1.07,;1.41,1.07,;-1.67,-1.6,;-3.21,-1.6,;-3.98,-.26,;-3.21,1.07,;-1.67,1.07,;-1.2,2.53,;-2.44,3.44,;-2.6,4.97,;-4.01,5.6,;-5.26,4.69,;-5.1,3.16,;-3.69,2.53,;2.95,-1.6,;2.18,-2.93,;2.95,-4.26,;4.49,-4.26,;5.26,-5.6,;5.26,-2.93,;4.49,-1.6,)| | ||
Structure |