Reaction Details | |||
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Target | 5-hydroxytryptamine receptor 2A | ||
Ligand | BDBM180704 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Radioligand Binding Assay | ||
Ki | 2.453±n/a nM | ||
Citation | Gobbi, L; Jaeschke, G; Roche, O; Sarmiento, RM; Steward, L Dual modulators of 5HT2A and D3 receptors US Patent US8829029 Publication Date 9/9/2014 | ||
More Info.: | Get all data from this article, Assay Method | ||
5-hydroxytryptamine receptor 2A | |||
Name: | 5-hydroxytryptamine receptor 2A | ||
Synonyms: | 5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A | ||
Type: | undefined | ||
Mol. Mass.: | 52607.65 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P28223 | ||
Residue: | 471 | ||
Sequence: |
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BDBM180704 | |||
n/a | |||
Name | BDBM180704 | ||
Synonyms: | US8829029, 4D | ||
Type | Small organic molecule | ||
Emp. Form. | C29H37FN6O3 | ||
Mol. Mass. | 536.6409 | ||
SMILES | Fc1ccc2c(noc2c1)C1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2cnc(nc2)N2CCOCC2)CC1 |r,wU:19.24,wD:16.17,(-8.67,3.46,;-7.34,4.23,;-6,3.46,;-4.67,4.23,;-4.67,5.77,;-3.33,6.54,;-3.33,8.08,;-6,8.08,;-6,6.54,;-7.34,5.77,;-2,5.77,;-2,4.23,;-.67,3.46,;.67,4.23,;2,3.46,;2,1.92,;3.33,1.15,;3.33,-.39,;4.67,-1.16,;6,-.39,;6,1.15,;4.67,1.93,;7.34,-1.15,;7.34,-2.69,;8.67,-3.46,;6,-3.46,;4.67,-2.69,;3.33,-3.46,;3.33,-5,;4.67,-5.77,;6,-5,;2,-5.77,;.67,-5,;-.67,-5.77,;-.67,-7.31,;.67,-8.08,;2,-7.31,;.67,5.77,;-.67,6.54,)| | ||
Structure |