| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A2b |
|---|
| Ligand | BDBM191832 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Luciferase Assay |
|---|
| pH | 7.4±n/a |
|---|
| Temperature | 310.15±n/a K |
|---|
| EC50 | 1440±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Vakalopoulos, A; Meibom, D; Nell, P; Sussmeier, F; Albrecht-Kupper, B; Zimmermann, K; Keldenich, J; Schneider, D; Krenz, U Substituted dicyanopyridines and use thereof US Patent US9187428 Publication Date 11/17/2015 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine receptor A2b |
|---|
| Name: | Adenosine receptor A2b |
|---|
| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 36341.22 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 332 |
|---|
| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
|
|
|
|---|
| BDBM191832 |
|---|
| n/a |
|---|
| Name | BDBM191832 |
|---|
| Synonyms: | US9187428, 60 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H21N5O3S |
|---|
| Mol. Mass. | 459.52 |
|---|
| SMILES | CC(Sc1nc(N)c(C#N)c(-c2ccc(OCCO)cc2)c1C#N)c1cccc(c1)C(N)=O |w:1.0| |
|---|
| Structure | 
|
|---|
Search and Browse
