Reaction Details | |||
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Target | Cannabinoid receptor 1 | ||
Ligand | BDBM192526 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Radioligand Displacement Assay (CP55940) | ||
Ki | 6.21±n/a nM | ||
Citation | Maitra, R; Fulp, AB; Zhang, Y; Seltzman, HH Peripherally restricted diphenyl purine derivatives US Patent US9187480 Publication Date 11/17/2015 | ||
More Info.: | Get all data from this article, Assay Method | ||
Cannabinoid receptor 1 | |||
Name: | Cannabinoid receptor 1 | ||
Synonyms: | CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain) | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 52868.96 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P21554 | ||
Residue: | 472 | ||
Sequence: |
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BDBM192526 | |||
n/a | |||
Name | BDBM192526 | ||
Synonyms: | US9187480, N-{4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-1-phenylcyclohexyl}methanesulfonamide | ||
Type | Small organic molecule | ||
Emp. Form. | C30H27Cl2N5O2S | ||
Mol. Mass. | 592.539 | ||
SMILES | CS(=O)(=O)NC1(CCC(CC1)c1ncnc2n(c(nc12)-c1ccccc1Cl)-c1ccc(Cl)cc1)c1ccccc1 |(3.5,1.51,;2.17,2.28,;2.94,3.62,;1.4,3.62,;.83,1.51,;.44,.03,;-.9,.8,;-2.23,.03,;-2.23,-1.51,;-.9,-2.28,;.44,-1.51,;-3.56,-2.28,;-4.9,-1.51,;-6.23,-2.28,;-6.23,-3.82,;-4.9,-4.59,;-4.58,-6.1,;-3.05,-6.26,;-2.42,-4.85,;-3.56,-3.82,;-2.28,-7.59,;-3.05,-8.93,;-2.28,-10.26,;-.74,-10.26,;.03,-8.93,;-.74,-7.59,;.03,-6.26,;-5.67,-7.19,;-7.15,-6.79,;-8.24,-7.88,;-7.85,-9.37,;-8.93,-10.46,;-6.36,-9.77,;-5.27,-8.68,;1.92,-.37,;2.32,-1.86,;3.81,-2.26,;4.9,-1.17,;4.5,.32,;3.01,.72,)| | ||
Structure |