Reaction Details | |||
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Target | Cannabinoid receptor 2 | ||
Ligand | BDBM192525 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Radioligand Displacement Assay (CP55940) | ||
Ki | 1657±n/a nM | ||
Citation | Maitra, R; Fulp, AB; Zhang, Y; Seltzman, HH Peripherally restricted diphenyl purine derivatives US Patent US9187480 Publication Date 11/17/2015 | ||
More Info.: | Get all data from this article, Assay Method | ||
Cannabinoid receptor 2 | |||
Name: | Cannabinoid receptor 2 | ||
Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 39690.94 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P34972 | ||
Residue: | 360 | ||
Sequence: |
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BDBM192525 | |||
n/a | |||
Name | BDBM192525 | ||
Synonyms: | US9187480, 4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-1-phenylcyclohexan-1-amine | ||
Type | Small organic molecule | ||
Emp. Form. | C29H25Cl2N5 | ||
Mol. Mass. | 514.448 | ||
SMILES | NC1(CCC(CC1)c1ncnc2n(c(nc12)-c1ccccc1Cl)-c1ccc(Cl)cc1)c1ccccc1 |(.83,2.57,;.44,1.08,;-.9,1.85,;-2.23,1.08,;-2.23,-.46,;-.9,-1.23,;.44,-.46,;-3.56,-1.23,;-4.9,-.46,;-6.23,-1.23,;-6.23,-2.77,;-4.9,-3.54,;-4.58,-5.05,;-3.05,-5.21,;-2.42,-3.8,;-3.56,-2.77,;-2.28,-6.54,;-3.05,-7.88,;-2.28,-9.21,;-.74,-9.21,;.03,-7.88,;-.74,-6.54,;.03,-5.21,;-5.67,-6.14,;-7.15,-5.74,;-8.24,-6.83,;-7.85,-8.32,;-8.93,-9.4,;-6.36,-8.71,;-5.27,-7.62,;1.92,.68,;2.32,-.81,;3.81,-1.21,;4.9,-.12,;4.5,1.37,;3.01,1.77,)| | ||
Structure |