| Reaction Details |
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 | Report a problem with these data |
| Target | Cyclin-dependent kinase-like 2 |
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| Ligand | BDBM205483 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Competitive Binding Assay (KINOMEscan) |
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| Kd | 5100±n/a nM |
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| Citation |  Murphy, EA; Cheresh, DA; Arnold, LD Therapeutic methods and compositions involving allosteric kinase inhibition US Patent US9260417 Publication Date 2/16/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Cyclin-dependent kinase-like 2 |
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| Name: | Cyclin-dependent kinase-like 2 |
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| Synonyms: | 2.7.11.22 | CDKL2 | CDKL2_HUMAN | Protein kinase p56 KKIAMRE | Serine/threonine-protein kinase KKIAMRE |
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| Type: | n/a |
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| Mol. Mass.: | 56031.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q92772 |
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| Residue: | 493 |
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| Sequence: | MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
ENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSH
NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRL
PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQEL
QLKVQKDARNVSLSKKSQNRKKEKEKDDSLVEERKTLVVQDTNADPKIKDYKLFKIKGSK
IDGEKAEKGNRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLS
AVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLVSGPPLSD
DSGADLPQMEHQH
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| BDBM205483 |
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| n/a |
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| Name | BDBM205483 |
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| Synonyms: | US9260417, 6 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H16F3N7OS |
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| Mol. Mass. | 459.448 |
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| SMILES | CSc1nc(N)cc(Oc2ccc(cc2)-c2nnc(Nc3cccc(c3)C(F)(F)F)[nH]2)n1 |
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| Structure | 
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