| Reaction Details |
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 | Report a problem with these data |
| Target | Lactoperoxidase |
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| Ligand | BDBM217355 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | LPO/TPO Selectivity Assay |
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| IC50 | 40± 1 nM |
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| Citation |  Forbes, LV; Sjögren, T; Auchère, F; Jenkins, DW; Thong, B; Laughton, D; Hemsley, P; Pairaudeau, G; Turner, R; Eriksson, H; Unitt, JF; Kettle, AJ Potent reversible inhibition of myeloperoxidase by aromatic hydroxamates. J Biol Chem288:36636-47 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lactoperoxidase |
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| Name: | Lactoperoxidase |
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| Synonyms: | LPO | Lactoperoxidase (LPO) | PERL_BOVIN |
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| Type: | Enzyme |
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| Mol. Mass.: | 80659.97 |
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| Organism: | Bos taurus (Bovine) |
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| Description: | P80025 |
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| Residue: | 712 |
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| Sequence: | MWVCLQLPVFLASVTLFEVAASDTIAQAASTTTISDAVSKVKIQVNKAFLDSRTRLKTTL
SSEAPTTQQLSEYFKHAKGRTRTAIRNGQVWEESLKRLRRDTTLTNVTDPSLDLTALSWE
VGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQ
RKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNE
HSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAV
TSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTT
ARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAF
IQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDE
NYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQDKMVTSELRNKLFQ
PTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDL
YKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDS
LQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN
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| BDBM217355 |
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| n/a |
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| Name | BDBM217355 |
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| Synonyms: | 4-benzyl-2-hydroxybenzenecarbohydroxamic acid (HX2) |
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| Type | Small organic molecule |
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| Emp. Form. | C14H13NO3 |
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| Mol. Mass. | 243.2579 |
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| SMILES | ONC(=O)c1ccc(Cc2ccccc2)cc1O |
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| Structure | 
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