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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Poly [ADP-ribose] polymerase tankyrase-1 [1091-1325] | ||
| Ligand | BDBM231126 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Tankyrase Biochemical Assays | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 16600±n/a nM | ||
| Comments | extracted | ||
| Citation |  Bregman, H; Buchanan, JL; Chakka, N; Dimauro, EF; Gunaydin, H; Guzman-Perez, A; Hua, Z; Huang, H; Huang, X; Martin, MW; Patel, VF Oxazolidinone compounds and derivatives thereof US Patent US9340549 Publication Date 5/17/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Poly [ADP-ribose] polymerase tankyrase-1 [1091-1325] | |||
| Name: | Poly [ADP-ribose] polymerase tankyrase-1 [1091-1325] | ||
| Synonyms: | PARP5A | PARPL | TIN1 | TINF1 | TNKS | TNKS1 | TNKS1_HUMAN | Tankyrase-1 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 26714.90 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O95271[1091-1325] | ||
| Residue: | 235 | ||
| Sequence: |
| ||
| BDBM231126 | |||
| n/a | |||
| Name | BDBM231126 | ||
| Synonyms: | US9340549, 151 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H28N4O3 | ||
| Mol. Mass. | 396.4827 | ||
| SMILES | Cn1cncc1C(=O)N[C@H]1CC[C@@H](CC1)N1[C@@H](c2ccccc2)C(C)(C)OC1=O |r,wU:16.18,9.9,wD:12.16,(5.04,4.81,;5.81,3.48,;7.27,3,;7.27,1.46,;5.81,.99,;4.9,2.23,;3.36,2.23,;2.59,3.56,;2.59,.9,;1.05,.9,;.28,-.44,;-1.26,-.44,;-2.03,.9,;-1.26,2.23,;.28,2.23,;-3.57,.9,;-4.47,-.35,;-4.07,-1.84,;-5.16,-2.92,;-4.77,-4.41,;-3.28,-4.81,;-2.19,-3.72,;-2.59,-2.23,;-5.94,.13,;-7.27,-.64,;-6.71,-1.21,;-5.94,1.67,;-4.47,2.14,;-3.7,3.48,)| | ||
| Structure | 
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