| Reaction Details |
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 | Report a problem with these data |
| Target | Poly [ADP-ribose] polymerase tankyrase-2 [946-1162] |
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| Ligand | BDBM50444585 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Tankyrase Biochemical Assays |
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| Temperature | 298.15±n/a K |
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| IC50 | 25.9±n/a nM |
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| Comments | extracted |
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| Citation |  Bregman, H; Buchanan, JL; Chakka, N; Dimauro, EF; Gunaydin, H; Guzman-Perez, A; Hua, Z; Huang, H; Huang, X; Martin, MW; Patel, VF Oxazolidinone compounds and derivatives thereof US Patent US9340549 Publication Date 5/17/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Poly [ADP-ribose] polymerase tankyrase-2 [946-1162] |
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| Name: | Poly [ADP-ribose] polymerase tankyrase-2 [946-1162] |
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| Synonyms: | PARP5B | TANK2 | TNKL | TNKS2 | TNKS2_HUMAN | Tankyrase-2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 24581.05 |
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| Organism: | Homo sapiens (Human) |
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| Description: | aa 946-1162 |
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| Residue: | 217 |
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| Sequence: | LNTSGSGTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKL
WERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENS
SKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSV
TGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPEG
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| BDBM50444585 |
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| n/a |
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| Name | BDBM50444585 |
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| Synonyms: | CHEMBL3099720 | US9340549, 65 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H23N5O2 |
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| Mol. Mass. | 437.4931 |
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| SMILES | CC1(C)OC(=O)N([C@H]1c1ccccc1)c1ccc(cc1)-c1cnc(N)c(c1)-c1ncccn1 |r| |
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| Structure | 
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