| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin E |
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| Ligand | BDBM234517 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence Resonance Energy Transfer (FRET) Assay |
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| pH | 4±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | 4010±n/a nM |
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| Comments | extracted |
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| Citation |  Chen, X; Ding, K; Meyers, MJ; Tortorella, MD; Xu, J Compositions and methods for the treatment of malaria US Patent US9353089 Publication Date 5/31/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Cathepsin E |
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| Name: | Cathepsin E |
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| Synonyms: | 3.4.23.34 | CATE_HUMAN | CTSE | Cathepsin E form I | Cathepsin E form II |
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| Type: | Enzyme |
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| Mol. Mass.: | 43298.99 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14091 |
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| Residue: | 396 |
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| Sequence: | MKTLLLLLLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESC
SMDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRF
QPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAE
FDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSH
FSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNA
IGAAPVDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDI
HPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPAVP
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| BDBM234517 |
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| n/a |
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| Name | BDBM234517 |
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| Synonyms: | US9353089, 171 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H28N4O2 |
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| Mol. Mass. | 440.5368 |
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| SMILES | COc1ccc(cc1)C1(NC(=N)N(C2CCCCC2)C1=O)c1cccc(c1)-c1cccnc1 |
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| Structure | 
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