| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-glucuronidase |
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| Ligand | BDBM152586 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | β-Glucuronidase Inhibition Assay |
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| pH | 7±0 |
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| Temperature | 310.15±0 K |
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| IC50 | 4.84e+4±n/a nM |
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| Citation |  Choudhary, MI; Zafar, S; Khan, NT; Ahmad, S; Noreen, S; Marasini, BP; Al-Khedhairy, AA; Atta-Ur-Rahman, null Biotransformation of dehydroepiandrosterone with Macrophomina phaseolina and ß-glucuronidase inhibitory activity of transformed products. J Enzyme Inhib Med Chem27:348-55 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-glucuronidase |
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| Name: | Beta-glucuronidase |
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| Synonyms: | β-Glucuronidase | BGLR_ECOLI | Beta-glucuronidase (EcGUS) | gurA | gusA | uidA |
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| Type: | Protein |
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| Mol. Mass.: | 68431.57 |
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| Organism: | Escherichia coli (Enterobacteria) |
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| Description: | P05804 |
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| Residue: | 603 |
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| Sequence: | MLRPVETPTREIKKLDGLWAFSLDRENCGIDQRWWESALQESRAIAVPGSFNDQFADADI
RNYAGNVWYQREVFIPKGWAGQRIVLRFDAVTHYGKVWVNNQEVMEHQGGYTPFEADVTP
YVIAGKSVRITVCVNNELNWQTIPPGMVITDENGKKKQSYFHDFFNYAGIHRSVMLYTTP
NTWVDDITVVTHVAQDCNHASVDWQVVANGDVSVELRDADQQVVATGQGTSGTLQVVNPH
LWQPGEGYLYELCVTAKSQTECDIYPLRVGIRSVAVKGEQFLINHKPFYFTGFGRHEDAD
LRGKGFDNVLMVHDHALMDWIGANSYRTSHYPYAEEMLDWADEHGIVVIDETAAVGFNLS
LGIGFEAGNKPKELYSEEAVNGETQQAHLQAIKELIARDKNHPSVVMWSIANEPDTRPQG
AREYFAPLAEATRKLDPTRPITCVNVMFCDAHTDTISDLFDVLCLNRYYGWYVQSGDLET
AEKVLEKELLAWQEKLHQPIIITEYGVDTLAGLHSMYTDMWSEEYQCAWLDMYHRVFDRV
SAVVGEQVWNFADFATSQGILRVGGNKKGIFTRDRKPKSAAFLLQKRWTGMNFGEKPQQG
GKQ
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| BDBM152586 |
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| n/a |
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| Name | BDBM152586 |
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| Synonyms: | D-Saccharic acid 1,4 lactone | D-Saccharic acid 1,4-lactone | D-Saccharic acid 1,4-lactone | D-saccharic acid-1,4-lactone |
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| Type | Small organic molecule |
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| Emp. Form. | C6H8O7 |
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| Mol. Mass. | 192.1235 |
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| SMILES | OC(C1OC(=O)C(O)C1O)C(O)=O |
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| Structure | 
|
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