BDBM152586 D-Saccharic acid 1,4 lactone::D-Saccharic acid 1,4-lactone::D-Saccharic acid 1,4-lactone ::D-saccharic acid-1,4-lactone
SMILES: OC(C1OC(=O)C(O)C1O)C(O)=O
InChI Key: InChIKey=XECPAIJNBXCOBO-UHFFFAOYSA-N
Data: 5 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-glucuronidase (β-glucuronidase) (Bos taurus (Bovine)) | BDBM152586 (D-Saccharic acid 1,4 lactone | D-Saccharic acid 1,...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.84E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Teknologi MARA (UiTM) | Assay Description β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr... | Bioorg Chem 61: 36-44 (2015) Article DOI: 10.1016/j.bioorg.2015.05.010 BindingDB Entry DOI: 10.7270/Q2HH6HTP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-glucuronidase (β-glucuronidase) (Bos taurus (Bovine)) | BDBM152586 (D-Saccharic acid 1,4 lactone | D-Saccharic acid 1,...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.84E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Teknologi MARA | Assay Description β-glucuronidase activity was determined by measuring absorbance at 405 nm of p-nitrophenol formed substrate by spectrophotometric method. 250 µL... | Bioorg Chem 68: 15-22 (2016) Article DOI: 10.1016/j.bioorg.2016.07.002 BindingDB Entry DOI: 10.7270/Q2542MCP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-glucuronidase (EcGUS) (Escherichia coli (Enterobacteria)) | BDBM152586 (D-Saccharic acid 1,4 lactone | D-Saccharic acid 1,...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.84E+4 | n/a | n/a | n/a | n/a | 7.0 | 37 |
University of Karachi | Assay Description β-Glucuronidase inhibitory activity was evaluated by a biochemical assay, based on the measurement of the absorbance of p-nitrophenol at 405 nm,... | J Enzyme Inhib Med Chem 27: 348-55 (2012) Article DOI: 10.3109/14756366.2011.590804 BindingDB Entry DOI: 10.7270/Q2N29VV5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
beta-Glucuronidase (β-glucuronidase) (Homo sapiens (Human)) | BDBM152586 (D-Saccharic acid 1,4 lactone | D-Saccharic acid 1,...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | n/a | n/a | 4.84E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
Universiti Teknologi MARA | Assay Description β-glucuronidase activity was determined in accordance to method used by Taha et al. [Taha et al., Bioorg. Med. Chem., 23:7394-7404] by measuring... | Bioorg Chem 72: 323-332 (2017) BindingDB Entry DOI: 10.7270/Q28051GP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
beta-Glucuronidase (β-glucuronidase) (Homo sapiens (Human)) | BDBM152586 (D-Saccharic acid 1,4 lactone | D-Saccharic acid 1,...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.84E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Teknologi MARA | Assay Description β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr... | Bioorg Chem 68: 56-63 (2016) Article DOI: 10.1016/j.bioorg.2016.07.008 BindingDB Entry DOI: 10.7270/Q2RV0MGS | |||||||||||
More data for this Ligand-Target Pair |