| Reaction Details |
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 | Report a problem with these data |
| Target | Prothrombin |
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| Ligand | BDBM294039 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Prothrombin Assay |
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| pH | 7.4±n/a |
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| Ki | 0.470±n/a nM |
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| Comments | extracted |
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| Citation |  Chen, S; Ding, Z; Gong, G; Yan, X; Huang, W; Guo, F; Duan, B; Gao, R; Zhou, P; Lu, X; Dong, G Preparation method for benzoxazoleoxazine ketone compound and intermediate and crystal form thereof US Patent US10106557 Publication Date 10/23/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Prothrombin |
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| Name: | Prothrombin |
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| Synonyms: | Activation peptide fragment 1 | Activation peptide fragment 2 | Coagulation factor II | F2 | Prothrombin precursor | THRB_HUMAN | Thrombin heavy chain | Thrombin light chain |
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| Type: | Protein |
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| Mol. Mass.: | 70029.57 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00734 |
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| Residue: | 622 |
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| Sequence: | MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLEREC
VEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHV
NITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQE
CSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASA
QAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETG
DGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYI
DGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEN
DLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHP
VCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDST
RIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKY
GFYTHVFRLKKWIQKVIDQFGE
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| BDBM294039 |
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| n/a |
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| Name | BDBM294039 |
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| Synonyms: | Process 1 | US10106557, Compound 1 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H18N2O5 |
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| Mol. Mass. | 342.3459 |
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| SMILES | Oc1cc(ccc1NC(=O)OCc1ccccc1)N1CCOCC1=O |
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| Structure | 
|
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