| Reaction Details |
|---|
 | Report a problem with these data |
| Target | cAMP-dependent protein kinase catalytic subunit alpha |
|---|
| Ligand | BDBM258599 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Competition Binding Assay |
|---|
| Temperature | 298.15±n/a K |
|---|
| IC50 | 7.88±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Akama, T; Jarnagin, K; Zhang, Y; Zhou, Y; Plattner, JJ; Sullivan, DC Boron-containing small molecules US Patent US9493490 Publication Date 11/15/2016 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| cAMP-dependent protein kinase catalytic subunit alpha |
|---|
| Name: | cAMP-dependent protein kinase catalytic subunit alpha |
|---|
| Synonyms: | KAPCA_HUMAN | PKA C-alpha | PKACA | PRKACA | cAMP-dependent protein kinase (PKA) | cAMP-dependent protein kinase catalytic (PKA) | cAMP-dependent protein kinase catalytic subunit alpha | cAMP-dependent protein kinase catalytic subunit alpha (PKA) | cAMP-dependent protein kinase catalytic subunit alpha (PKACA) | cAMP-dependent protein kinase catalytic subunit alpha (PKAc) | cAMP-dependent protein kinase catalytic subunit alpha isoform 1 | cAMP-dependent protein kinase, alpha-catalytic subunit |
|---|
| Type: | Enzyme Catalytic Subunit |
|---|
| Mol. Mass.: | 40598.73 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 351 |
|---|
| Sequence: | MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVML
VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV
MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY
IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF
ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT
TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF
|
|
|
|---|
| BDBM258599 |
|---|
| n/a |
|---|
| Name | BDBM258599 |
|---|
| Synonyms: | US9493490, Example 11 | US9493490, L | US9493490, tert-butyl 2-fluoro-3-(1-hydroxy-7-methyl-1,3-dihydrobenzo[c][1,2]oxaborol-6-yloxy)benzylcarbamate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H23BFNO5 |
|---|
| Mol. Mass. | 387.21 |
|---|
| SMILES | Cc1c2B(O)OCc2ccc1Oc1cccc(CNC(=O)OC(C)(C)C)c1F |
|---|
| Structure | 
|
|---|
Search and Browse
