| Reaction Details |
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 | Report a problem with these data |
| Target | Poly [ADP-ribose] polymerase tankyrase-1 [1091-1325] |
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| Ligand | BDBM259541 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Biochemical Assay |
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| IC50 | 1.3±n/a nM |
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| Citation |  Bregman, H; Buchanan, JL; Chakka, N; Dimauro, EF; Gunaydin, H; Guzman-Perez, A; Hua, Z; Huang, X Quinazolinone compounds and derivatives thereof US Patent US9505749 Publication Date 11/29/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Poly [ADP-ribose] polymerase tankyrase-1 [1091-1325] |
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| Name: | Poly [ADP-ribose] polymerase tankyrase-1 [1091-1325] |
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| Synonyms: | PARP5A | PARPL | TIN1 | TINF1 | TNKS | TNKS1 | TNKS1_HUMAN | Tankyrase-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 26714.90 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O95271[1091-1325] |
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| Residue: | 235 |
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| Sequence: | QGTNPYLTFHCVNQGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRI
QKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGA
GIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTMKMAH
APPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKPEAPSQTATAAEQ
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| BDBM259541 |
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| n/a |
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| Name | BDBM259541 |
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| Synonyms: | US9505749, 52 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H24F3N5O3 |
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| Mol. Mass. | 499.485 |
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| SMILES | FC(F)(F)c1ccc2n(C3CCN(CC3)C(=O)CCCc3nc4ccccc4c(=O)[nH]3)c(=O)[nH]c2c1 |
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| Structure | 
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