| Reaction Details |
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 | Report a problem with these data |
| Target | Uracil-DNA glycosylase |
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| Ligand | BDBM294514 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Processive DNA synthesis assay |
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| pH | 7.5±n/a |
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| EC50 | 13900±n/a nM |
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| Comments | extracted |
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| Citation |  Ricciardi, RP; Reitz, AB; Parker, MH; Baugh, SD; Nuth, M; Guan, H Antivirals against molluscum contagiosum virus US Patent US10112895 Publication Date 10/30/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Uracil-DNA glycosylase |
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| Name: | Uracil-DNA glycosylase |
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| Synonyms: | OPG116 | UDG | UNG | UNG_VACCW |
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| Type: | PROTEIN |
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| Mol. Mass.: | 25071.48 |
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| Organism: | Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strainWR)) |
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| Description: | ChEMBL_747132 |
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| Residue: | 218 |
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| Sequence: | MNSVTVSHAPYTITYHDDWEPVMSQLVEFYNEVASWLLRDETSPIPDKFFIQLKQPLRNK
RVCVCGIDPYPKDGTGVPFESPNFTKKSIKEIASSISRLTGVIDYKGYNLNIIDGVIPWN
YYLSCKLGETKSHAIYWDKISKLLLQHITKHVSVLYCLGKTDYSNIRAKLESPVTTIVGY
HPAARDRQFEKDRSFEIINVLLELDNKAPINWAQGFIY
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| BDBM294514 |
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| n/a |
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| Name | BDBM294514 |
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| Synonyms: | 5-[[2-[(4- fluorophenyl)methoxy]phenyl] methylamino]-1,3- dihydrobenzimidazol-2-one | US10112895, Compound 6 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H18FN3O2 |
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| Mol. Mass. | 363.3849 |
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| SMILES | Fc1ccc(COc2ccccc2CNc2ccc3[nH]c(=O)[nH]c3c2)cc1 |
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| Structure | 
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