| Reaction Details |
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 | Report a problem with these data |
| Target | Bromodomain-containing protein 4 [1-477] |
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| Ligand | BDBM425779 |
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| Substrate/Competitor | n/a |
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| IC50 | <1000±n/a nM |
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| Citation |  Zhang, J; Buell, J; Chan, K; Ibrahim, PN; Lin, J; Pham, P; Shi, S; Spevak, W; Wu, G; Wu, J Heterocyclic compounds and uses thereof US Patent US10519177 Publication Date 12/31/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Bromodomain-containing protein 4 [1-477] |
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| Name: | Bromodomain-containing protein 4 [1-477] |
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| Synonyms: | BRD4 | BRD4_HUMAN | Bromodomain-containing protein 4 (BRD4 (aa 1-477) | Bromodomain-containing protein 4 (aa 1-477) | HUNK1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 53061.90 |
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| Organism: | Homo sapiens (Human) |
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| Description: | aa (1-477) |
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| Residue: | 477 |
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| Sequence: | MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQT
NQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYW
NAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRG
RGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMT
VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI
DPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGI
LKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGA
DVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPT
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| BDBM425779 |
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| n/a |
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| Name | BDBM425779 |
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| Synonyms: | N-[4-[6-(3,5-dimethylisoxazol-4- yl)-1-[(1S)-1-(2- pyridyl)ethyl]pyrrolo[3,2-b]pyridin- 3-yl]phenyl]methanesulfonamide | US10519177, Compound P-0979 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H25N5O3S |
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| Mol. Mass. | 487.573 |
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| SMILES | C[C@@H](c1ccccn1)n1cc(-c2ccc(NS(C)(=O)=O)cc2)c2ncc(cc12)-c1c(C)noc1C |r| |
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| Structure | 
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