| Reaction Details |
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 | Report a problem with these data |
| Target | N-acylethanolamine-hydrolyzing acid amidase |
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| Ligand | BDBM430273 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | h-NAAA Assay |
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| IC50 | 298±20 nM |
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| Citation |  Piomelli, D; Scarpelli, R; Migliore, M; Heim, R; Garcia-Guzmàn, M Piperazinyl methanone NAAA inhibitors US Patent US10556892 Publication Date 2/11/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| N-acylethanolamine-hydrolyzing acid amidase |
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| Name: | N-acylethanolamine-hydrolyzing acid amidase |
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| Synonyms: | ASAH-like protein | ASAHL | Acid ceramidase-like protein | N-acylethanolamine-hydrolyzing acid amidase | N-acylsphingosine amidohydrolase-like | N-acylsphingosine-amidohydrolase | NAAA | NAAA_HUMAN | PLT |
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| Type: | Enzyme |
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| Mol. Mass.: | 40073.12 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q02083 |
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| Residue: | 359 |
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| Sequence: | MRTADREARPGLPSLLLLLLAGAGLSAASPPAAPRFNVSLDSVPELRWLPVLRHYDLDLV
RAAMAQVIGDRVPKWVHVLIGKVVLELERFLPQPFTGEIRGMCDFMNLSLADCLLVNLAY
ESSVFCTSIVAQDSRGHIYHGRNLDYPFGNVLRKLTVDVQFLKNGQIAFTGTTFIGYVGL
WTGQSPHKFTVSGDERDKGWWWENAIAALFRRHIPVSWLIRATLSESENFEAAVGKLAKT
PLIADVYYIVGGTSPREGVVITRNRDGPADIWPLDPLNGAWFRVETNYDHWKPAPKEDDR
RTSAIKALNATGQANLSLEALFQILSVVPVYNNFTIYTTVMSAGSPDKYMTRIRNPSRK
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| BDBM430273 |
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| n/a |
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| Name | BDBM430273 |
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| Synonyms: | US10556892, Compound 9 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H20FN3O3S2 |
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| Mol. Mass. | 433.52 |
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| SMILES | CCS(=O)(=O)c1ccccc1C(=O)N1CCN(CC1)c1nc2cccc(F)c2s1 |
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| Structure | 
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