| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase 17B |
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| Ligand | BDBM441863 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Activity Inhibition Assay |
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| IC50 | 180±n/a nM |
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| Citation |  Lee, K; Choi, G; Lee, NR; Park, SJ; Jung, ME; Kim, SJ; Yang, K; Lee, J Substituted pyrimidines for preventing or treating cancer and inflammatory diseases US Patent US10647686 Publication Date 5/12/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase 17B |
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| Name: | Serine/threonine-protein kinase 17B |
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| Synonyms: | DRAK2 | ST17B_HUMAN | STK17B | Serine/threonine-protein kinase 17B | Serine/threonine-protein kinase 17B (STK17B) |
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| Type: | Enzyme |
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| Mol. Mass.: | 42332.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O94768 |
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| Residue: | 372 |
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| Sequence: | MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYA
AKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFS
LCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDF
GMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDN
QETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFEN
LFHPEETSSSSQTQDHSVRSSEDKTSKSSCNGTCGDREDKENIPEDSSMVSKRFRFDDSL
PNPHELVSDLLC
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| BDBM441863 |
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| n/a |
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| Name | BDBM441863 |
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| Synonyms: | US10647686, Example (10) |
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| Type | Small organic molecule |
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| Emp. Form. | C19H20ClN5O |
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| Mol. Mass. | 369.848 |
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| SMILES | NCCCNc1nc(Nc2ccc(Oc3ccccc3)cc2)ncc1Cl |
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| Structure | 
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