| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM501675 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radioligand Binding Competition Assay |
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| IC50 | 57.0±n/a nM |
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| Citation |  Pham, SM; Chen, J; Ansari, A; Jadhavar, PS; Patil, VS; Khan, F; Ramachandran, SA; Agarwal, AK; Chakravarty, S Heterocyclic compounds as adenosine antagonists US Patent US11028058 Publication Date 6/8/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44716.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29274 |
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| Residue: | 412 |
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| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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| BDBM501675 |
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| n/a |
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| Name | BDBM501675 |
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| Synonyms: | US11028058, Compound 1.1 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H12ClN3O |
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| Mol. Mass. | 297.739 |
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| SMILES | Nc1cnc(-c2ccc(O)c(Cl)c2)c(n1)-c1ccccc1 |
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| Structure | 
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