null

SMILES CN(CCCCc1ccccc1)CCC(O)(P(O)(O)=O)P(O)(O)=O

InChI Key InChIKey=VFLFYDXGZMGUAF-UHFFFAOYSA-N

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 25290   

TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Illinois at Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM25290(CHEMBL56073 | bisphosphonate, 39 | {1-hydroxy-3-[m...)copy SMILEScopy InChI
Affinity DataKi:  46nMAssay Description:Binding affinity towards farnesyl Pyrophosphate Synthase using [14C]- isopentenyl pyrophosphate as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M93Z8PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Illinois at Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM25290(CHEMBL56073 | bisphosphonate, 39 | {1-hydroxy-3-[m...)copy SMILEScopy InChI
Affinity DataIC50: 490nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M93Z8PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University of Illinois at Urbana - Champaign

Curated by ChEMBL
LigandPNGBDBM25290(CHEMBL56073 | bisphosphonate, 39 | {1-hydroxy-3-[m...)copy SMILEScopy InChI
Affinity DataIC50: 2.45E+5nMAssay Description:Inhibition of Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0HW7PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Illinois at Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM25290(CHEMBL56073 | bisphosphonate, 39 | {1-hydroxy-3-[m...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Negative logarithm of inhibitory concentration against bone resorptionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78GHDPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Illinois at Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM25290(CHEMBL56073 | bisphosphonate, 39 | {1-hydroxy-3-[m...)copy SMILEScopy InChI
Affinity DataIC50: 490nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase expressed as #NAME? (M)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M93Z8PubMed
TargetFarnesyl diphosphate synthase(Escherichia coli K-12)
University of Illinois at Urbana - Champaign

Curated by ChEMBL
LigandPNGBDBM25290(CHEMBL56073 | bisphosphonate, 39 | {1-hydroxy-3-[m...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Escherichia coli FPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0HW7PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25290(CHEMBL56073 | bisphosphonate, 39 | {1-hydroxy-3-[m...)copy SMILEScopy InChI
Affinity DataIC50: 4.17E+3nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028PVTPubMed
TargetPolyprenyl synthetase family protein(Plasmodium falciparum (isolate 3D7))
University of Illinois at Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM25290(CHEMBL56073 | bisphosphonate, 39 | {1-hydroxy-3-[m...)copy SMILEScopy InChI
Affinity DataIC50: 490nMAssay Description:Inhibitory activity against Leishmania major Farnesyl diphosphate synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN15N5PubMed