null
SMILES Nc1ncc2cc(c(N)nc2n1)-c1c(Br)cccc1Br
InChI Key InChIKey=HGIPWJYTPOHUGK-UHFFFAOYSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 3436
Affinity DataIC50: 5.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
TargetBiotin carboxylase(Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22...)
Achaogen Inc.
Curated by ChEMBL
Achaogen Inc.
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant N-terminal His-tagged Pseudomonas aeruginosa PAO1 biotin carboxylase expressed in Escherichia coli Rosetta(DE3) pLysS cells...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 8.0 T: 2°CAssay Description:Assays were performed in 384-well clear bottom plates (Corning; catalog no. 3702), that contained inhibitor solvated in DMSO. To each well of the pla...More data for this Ligand-Target Pair
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2WM1BR8PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2WM1BR8PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
Affinity DataIC50: 1.60E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair