Compile Data Set for Download or QSAR
Found 29 Enz. Inhib. hit(s) with Target = 'Biotin carboxylase'
TargetBiotin carboxylase(Escherichia coli (strain K12))
Pfizer

LigandPNGBDBM3436(6-(2,6-Dibromo-phenyl)-pyrido[2,3-d]pyrimidine-2,7...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 8.0 T: 2°CAssay Description:Assays were performed in 384-well clear bottom plates (Corning; catalog no. 3702), that contained inhibitor solvated in DMSO. To each well of the pla...More data for this Ligand-Target Pair
TargetBiotin carboxylase(Escherichia coli (strain K12))
Pfizer

LigandPNGBDBM32642(amino-oxazole, 2d)copy SMILEScopy InChI
Affinity DataIC50: 7nMpH: 8.0 T: 2°CAssay Description:Assays were performed in 384-well clear bottom plates (Corning; catalog no. 3702), that contained inhibitor solvated in DMSO. To each well of the pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BR8PubMed
TargetBiotin carboxylase(Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22...)
Achaogen Inc.

Curated by ChEMBL
LigandPNGBDBM50528527(CHEMBL4466052)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant N-terminal His-tagged Pseudomonas aeruginosa PAO1 biotin carboxylase expressed in Escherichia coli Rosetta(DE3) pLysS cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ14G4PubMed
TargetBiotin carboxylase(Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22...)
Achaogen Inc.

Curated by ChEMBL
LigandPNGBDBM50528526(CHEMBL4518489)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant N-terminal His-tagged Pseudomonas aeruginosa PAO1 biotin carboxylase expressed in Escherichia coli Rosetta(DE3) pLysS cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ14G4PubMed
TargetBiotin carboxylase(Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22...)
Achaogen Inc.

Curated by ChEMBL
LigandPNGBDBM50528519(CHEMBL4530311)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant N-terminal His-tagged Pseudomonas aeruginosa PAO1 biotin carboxylase expressed in Escherichia coli Rosetta(DE3) pLysS cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ14G4PubMed
TargetBiotin carboxylase(Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22...)
Achaogen Inc.

Curated by ChEMBL
LigandPNGBDBM50528516(CHEMBL4459017)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of recombinant N-terminal His-tagged Pseudomonas aeruginosa PAO1 biotin carboxylase expressed in Escherichia coli Rosetta(DE3) pLysS cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ14G4PubMed
TargetBiotin carboxylase(Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22...)
Achaogen Inc.

Curated by ChEMBL
LigandPNGBDBM50528524(CHEMBL4450292)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of recombinant N-terminal His-tagged Pseudomonas aeruginosa PAO1 biotin carboxylase expressed in Escherichia coli Rosetta(DE3) pLysS cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ14G4PubMed
TargetBiotin carboxylase(Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22...)
Achaogen Inc.

Curated by ChEMBL
LigandPNGBDBM50528522(CHEMBL4563086)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibition of recombinant N-terminal His-tagged Pseudomonas aeruginosa PAO1 biotin carboxylase expressed in Escherichia coli Rosetta(DE3) pLysS cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ14G4PubMed
TargetBiotin carboxylase(Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22...)
Achaogen Inc.

Curated by ChEMBL
LigandPNGBDBM50528520(CHEMBL4445287)copy SMILEScopy InChI
Affinity DataIC50: 93nMAssay Description:Inhibition of recombinant N-terminal His-tagged Pseudomonas aeruginosa PAO1 biotin carboxylase expressed in Escherichia coli Rosetta(DE3) pLysS cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ14G4PubMed
TargetBiotin carboxylase(Escherichia coli (strain K12))
Pfizer

LigandPNGBDBM32641(amino-oxazole, 2c)copy SMILEScopy InChI
Affinity DataIC50: 125nMpH: 8.0 T: 2°CAssay Description:Assays were performed in 384-well clear bottom plates (Corning; catalog no. 3702), that contained inhibitor solvated in DMSO. To each well of the pla...More data for this Ligand-Target Pair
TargetBiotin carboxylase(Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22...)
Achaogen Inc.

Curated by ChEMBL
LigandPNGBDBM50528518(CHEMBL4551132)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant N-terminal His-tagged Pseudomonas aeruginosa PAO1 biotin carboxylase expressed in Escherichia coli Rosetta(DE3) pLysS cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ14G4PubMed
TargetBiotin carboxylase(Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22...)
Achaogen Inc.

Curated by ChEMBL
LigandPNGBDBM50528523(CHEMBL4564355)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant N-terminal His-tagged Pseudomonas aeruginosa PAO1 biotin carboxylase expressed in Escherichia coli Rosetta(DE3) pLysS cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ14G4PubMed
TargetBiotin carboxylase(Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22...)
Achaogen Inc.

Curated by ChEMBL
LigandPNGBDBM50528515(CHEMBL4582507)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant N-terminal His-tagged Pseudomonas aeruginosa PAO1 biotin carboxylase expressed in Escherichia coli Rosetta(DE3) pLysS cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ14G4PubMed
TargetBiotin carboxylase(Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22...)
Achaogen Inc.

Curated by ChEMBL
LigandPNGBDBM3436(6-(2,6-Dibromo-phenyl)-pyrido[2,3-d]pyrimidine-2,7...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant N-terminal His-tagged Pseudomonas aeruginosa PAO1 biotin carboxylase expressed in Escherichia coli Rosetta(DE3) pLysS cells...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ14G4PubMed
TargetBiotin carboxylase(Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22...)
Achaogen Inc.

Curated by ChEMBL
LigandPNGBDBM50528525(CHEMBL4440951)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant N-terminal His-tagged Pseudomonas aeruginosa PAO1 biotin carboxylase expressed in Escherichia coli Rosetta(DE3) pLysS cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ14G4PubMed
TargetBiotin carboxylase(Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22...)
Achaogen Inc.

Curated by ChEMBL
LigandPNGBDBM3429(6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidine-2,7-...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant N-terminal His-tagged Pseudomonas aeruginosa PAO1 biotin carboxylase expressed in Escherichia coli Rosetta(DE3) pLysS cells...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ14G4PubMed
TargetBiotin carboxylase(Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22...)
Achaogen Inc.

Curated by ChEMBL
LigandPNGBDBM50528517(CHEMBL4464608)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant N-terminal His-tagged Pseudomonas aeruginosa PAO1 biotin carboxylase expressed in Escherichia coli Rosetta(DE3) pLysS cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ14G4PubMed
TargetBiotin carboxylase(Escherichia coli (strain K12))
Pfizer

LigandPNGBDBM32644(amino pyrimidine, 3c)copy SMILEScopy InChI
Affinity DataIC50: 333nMpH: 8.0 T: 2°CAssay Description:Assays were performed in 384-well clear bottom plates (Corning; catalog no. 3702), that contained inhibitor solvated in DMSO. To each well of the pla...More data for this Ligand-Target Pair
TargetBiotin carboxylase(Escherichia coli (strain K12))
Pfizer

LigandPNGBDBM32647(amino pyrimidine, 6b)copy SMILEScopy InChI
Affinity DataIC50: 334nMpH: 8.0 T: 2°CAssay Description:Assays were performed in 384-well clear bottom plates (Corning; catalog no. 3702), that contained inhibitor solvated in DMSO. To each well of the pla...More data for this Ligand-Target Pair
TargetBiotin carboxylase(Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22...)
Achaogen Inc.

Curated by ChEMBL
LigandPNGBDBM50528521(CHEMBL4520904)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:Inhibition of recombinant N-terminal His-tagged Pseudomonas aeruginosa PAO1 biotin carboxylase expressed in Escherichia coli Rosetta(DE3) pLysS cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ14G4PubMed
TargetBiotin carboxylase(Escherichia coli (strain K12))
Pfizer

LigandPNGBDBM32640(amino-oxazole, 2b)copy SMILEScopy InChI
Affinity DataIC50: 1.29E+3nMpH: 8.0 T: 2°CAssay Description:Assays were performed in 384-well clear bottom plates (Corning; catalog no. 3702), that contained inhibitor solvated in DMSO. To each well of the pla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BR8PubMed
TargetBiotin carboxylase(Escherichia coli (strain K12))
Pfizer

LigandPNGBDBM32649(amino imidazo-pyridinone, 8)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMpH: 8.0 T: 2°CAssay Description:Assays were performed in 384-well clear bottom plates (Corning; catalog no. 3702), that contained inhibitor solvated in DMSO. To each well of the pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BR8PubMed
TargetBiotin carboxylase(Escherichia coli (strain K12))
Pfizer

LigandPNGBDBM32648(amino pyrimidine, 7)copy SMILEScopy InChI
Affinity DataIC50: 8.20E+3nMpH: 8.0 T: 2°CAssay Description:Assays were performed in 384-well clear bottom plates (Corning; catalog no. 3702), that contained inhibitor solvated in DMSO. To each well of the pla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BR8PubMed
TargetBiotin carboxylase(Escherichia coli (strain K12))
Pfizer

LigandPNGBDBM32646(amino pyrimidine, 6a)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMpH: 8.0 T: 2°CAssay Description:Assays were performed in 384-well clear bottom plates (Corning; catalog no. 3702), that contained inhibitor solvated in DMSO. To each well of the pla...More data for this Ligand-Target Pair
TargetBiotin carboxylase(Escherichia coli (strain K12))
Pfizer

LigandPNGBDBM32639(amino-oxazole, 2)copy SMILEScopy InChI
Affinity DataIC50: 2.15E+4nMpH: 8.0 T: 2°CAssay Description:Assays were performed in 384-well clear bottom plates (Corning; catalog no. 3702), that contained inhibitor solvated in DMSO. To each well of the pla...More data for this Ligand-Target Pair
TargetBiotin carboxylase(Escherichia coli (strain K12))
Pfizer

LigandPNGBDBM32650(1,3,5-triazine-2,4-diamine, 4)copy SMILEScopy InChI
Affinity DataIC50: 2.54E+4nMpH: 8.0 T: 2°CAssay Description:Assays were performed in 384-well clear bottom plates (Corning; catalog no. 3702), that contained inhibitor solvated in DMSO. To each well of the pla...More data for this Ligand-Target Pair
TargetBiotin carboxylase(Escherichia coli (strain K12))
Pfizer

LigandPNGBDBM32645(amino pyrimidine, 6)copy SMILEScopy InChI
Affinity DataIC50: 5.93E+4nMpH: 8.0 T: 2°CAssay Description:Assays were performed in 384-well clear bottom plates (Corning; catalog no. 3702), that contained inhibitor solvated in DMSO. To each well of the pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BR8PubMed
TargetBiotin carboxylase(Escherichia coli (strain K12))
Pfizer

LigandPNGBDBM32643(amino pyrimidine ketone, 3)copy SMILEScopy InChI
Affinity DataIC50: 6.08E+4nMpH: 8.0 T: 2°CAssay Description:Assays were performed in 384-well clear bottom plates (Corning; catalog no. 3702), that contained inhibitor solvated in DMSO. To each well of the pla...More data for this Ligand-Target Pair
TargetBiotin carboxylase(Escherichia coli (strain K12))
Pfizer

LigandPNGBDBM32651(dihydro-2H-purin-6-amine, 5)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+6nMpH: 8.0 T: 2°CAssay Description:Assays were performed in 384-well clear bottom plates (Corning; catalog no. 3702), that contained inhibitor solvated in DMSO. To each well of the pla...More data for this Ligand-Target Pair