null

SMILES COc1cccc(c1)-c1nc(Nc2ccc(F)cc2)c2cccnc2n1

InChI Key InChIKey=NJVMWTULVYFABU-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263351   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Pharmaceutical Institute , University of Bonn , An der Immenburg 4 , 53121 Bonn , Germany.

Curated by ChEMBL
LigandPNGBDBM50263351(CHEMBL4091528)copy SMILEScopy InChI
Affinity DataIC50: 425nMAssay Description:Inhibition of human ABCG2 expressed in MDCK2 cells assessed as increase in accumulation of Hoechst 33342 preincubated for 30 mins followed by Hoechst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5BXMPubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Pharmaceutical Institute , University of Bonn , An der Immenburg 4 , 53121 Bonn , Germany.

Curated by ChEMBL
LigandPNGBDBM50263351(CHEMBL4091528)copy SMILEScopy InChI
Affinity DataEC50:  4nMAssay Description:Activation of recombinant human ABCG2 ATPase activity expressed in baculovirus infected High five insect cell membranes after 20 mins by ascorbic aci...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5BXMPubMed