Found 2 Enz. Inhib. hit(s) with Target = 'Broad substrate specificity ATP-binding cassette transporter ABCG2' and Ligand = 'BDBM50263351' TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Pharmaceutical Institute , University of Bonn , An der Immenburg 4 , 53121 Bonn , Germany.
Curated by ChEMBL
Pharmaceutical Institute , University of Bonn , An der Immenburg 4 , 53121 Bonn , Germany.
Curated by ChEMBL
Affinity DataIC50: 425nMAssay Description:Inhibition of human ABCG2 expressed in MDCK2 cells assessed as increase in accumulation of Hoechst 33342 preincubated for 30 mins followed by Hoechst...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Pharmaceutical Institute , University of Bonn , An der Immenburg 4 , 53121 Bonn , Germany.
Curated by ChEMBL
Pharmaceutical Institute , University of Bonn , An der Immenburg 4 , 53121 Bonn , Germany.
Curated by ChEMBL
Affinity DataEC50: 4nMAssay Description:Activation of recombinant human ABCG2 ATPase activity expressed in baculovirus infected High five insect cell membranes after 20 mins by ascorbic aci...More data for this Ligand-Target Pair
