null

SMILES COc1cc(O)c2c(CCCC(=O)C(=O)C(O)CCC[C@H](C)OC2=O)c1

InChI Key InChIKey=CZVAYVPOBIDGLC-ZSOXZCCMSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 47 hits for monomerid = 50413752   

TargetEphrin type-B receptor 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EPHB4 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 60nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z777ZPubMed
TargetMAP kinase-activated protein kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 640nMAssay Description:Inhibition of MK5 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RET by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of TYK2 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 950nMAssay Description:Inhibition of ERK2 by Caliper mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetAurora kinase A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora A kinase by Caliper mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Axl by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BTK by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ZAP70 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetEphrin type-A receptor 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EPHA4 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HGFR by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGF1R by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK1 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK2 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK3 by Caliper mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetSerine/threonine-protein kinase N1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PKN1 by Caliper mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetSerine/threonine-protein kinase N2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PKN2 by Caliper mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ROCK2 by Caliper mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 763nMAssay Description:Inhibition of ALK by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetInsulin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of INSR by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of MEK2 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of VEGFR2 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p38alpha by Caliper mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK2A by Caliper mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HER2 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PKAalpha by Caliper mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 303nMAssay Description:Inhibition of cKIT by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GSK3-beta by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDK1 by Caliper mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR3 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of VEGFR2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant FLT3 ITD mutant (unknown origin) by RBC kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53NG1PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of recombinant FLT3 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53NG1PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant FLT3 D835Y mutant (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53NG1PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
AMRI

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7PDBPubMed
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 125nMAssay Description:Inhibition of human ALK1 using casein as substrate in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ63S4PubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human FLT4 using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ63S4PubMed
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human MEK2 using ERK2 as substrate in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ63S4PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human FLT3 using EAIYAAPFAKKK peptide as substrate in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ63S4PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human KDR using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ63S4PubMed
TargetDual specificity mitogen-activated protein kinase kinase 6(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 388nMAssay Description:Inhibition of human MKK6 using p38a as substrate in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ63S4PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human FLT3 using EAIYAAPFAKKK substrate and [gamma-33P]-ATP by radiometric biochemical kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41VR7PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human VEGFR2 using poly[Glu:Tyr] (4:1) substrate and [gamma-33P]-ATP by radiometric biochemical kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41VR7PubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 0.730nMAssay Description:Inhibition of human VEGFR3 using poly[Glu:Tyr] (4:1) substrate and [gamma-33P]-ATP by radiometric biochemical kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41VR7PubMed
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 325nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z777ZPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
AMRI

Curated by ChEMBL
LigandPNGBDBM50413752(CHEMBL2012519 | L-783277)copy SMILEScopy InChI
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of LCK by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NWTPubMed