Compile Data Set for Download or QSAR
Found 226 Enz. Inhib. hit(s) with Target = 'Transcription initiation factor TFIID subunit 1 [1504-1635]'
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346431(US10202378, Example 44 | ethyl 2,6-dimethyl-7-oxo-...)copy SMILES
Affinity DataIC50: 17nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346545(2-methylbutyl 4-(3-hydroxy-3-methyl-but-1-ynyl)-2,...)copy SMILES
Affinity DataIC50: 19.4nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346540((1-acetyl-4-piperidyl)methyl4-(3-hydroxy-3-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 20.1nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346476(US10202378, Example 89 | US10202378, Example 93a |...)copy SMILES
Affinity DataIC50: 21.4nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346517(US10202378, Example 121 | o-tolylmethyl 4-(3-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 21.5nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346428(US10202378, Example 41 | ethyl 2,6-dimethyl-7-oxo-...)copy SMILES
Affinity DataIC50: 21.5nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346561((3-amino-1,1-dimethyl-propyl) 4-(3-hydroxy-3-methy...)copy SMILEScopy InChI
Affinity DataIC50: 21.7nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346405(US10202378, Example 20 | ethyl 4-[2-(1-hydroxycycl...)copy SMILEScopy InChI
Affinity DataIC50: 21.9nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346467(US10202378, Example 80 | ethyl 4-(3-hydroxy-3-phen...)copy SMILES
Affinity DataIC50: 22.6nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346549(US10202378, Example 153 | cyclohexylmethyl 4-(3-hy...)copy SMILEScopy InChI
Affinity DataIC50: 22.6nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346544(US10202378, Example 148 | cyclopentylmethyl 4-(3-h...)copy SMILEScopy InChI
Affinity DataIC50: 23.7nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346509((2-methoxyphenyl)methyl-4-(3-hydroxy-3-methyl-but-...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346515((2-fluorophenyl)methyl 4-(3-hydroxy-3-methyl-but-1...)copy SMILEScopy InChI
Affinity DataIC50: 26.7nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346530((2-cyano-1,1-dimethyl-ethyl)-4-(3-cyclopropyl-3-hy...)copy SMILES
Affinity DataIC50: 26.8nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346559((2-cyano-1,1-dimethyl-ethyl)4-(3-hydroxy-3-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 27.3nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346496(US10202378, Example 100 | ethyl 2,6-dimethyl-7-oxo...)copy SMILES
Affinity DataIC50: 27.3nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346484(3-(5-isopropyl-1,3,4-oxadiazol-2-yl)-2,6-dimethyl-...)copy SMILES
Affinity DataIC50: 27.6nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346512(US10202378, Example 116 | [2-(trifluoromethyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 27.7nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346575(4-(3-cyclopropyl-3-hydroxy-but-1-ynyl)-3-(5-isobut...)copy SMILES
Affinity DataIC50: 29.2nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346506((2-cyanophenyl)methyl 4-(3-hydroxy-3-methyl-but-1-...)copy SMILEScopy InChI
Affinity DataIC50: 29.4nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346591(4-(3-hydroxy-3-methyl-but-1-ynyl)-3-(5-isopropyl-1...)copy SMILEScopy InChI
Affinity DataIC50: 29.4nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346528(US10202378, Example 132 | isobutyl 4-(3-hydroxy-3-...)copy SMILEScopy InChI
Affinity DataIC50: 29.9nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346404(US10202378, Example 19 | ethyl 4-[3-(3-cyanophenyl...)copy SMILES
Affinity DataIC50: 30.3nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346546(2,2-dimethylpropyl 4-(3-hydroxy-3-methyl-but-1-yny...)copy SMILEScopy InChI
Affinity DataIC50: 30.4nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346490(4-(3-cyclopropyl-3-hydroxy-but-1-ynyl)-3-[5-[(dime...)copy SMILES
Affinity DataIC50: 30.8nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346529(US10202378, Example 133 | tert-butyl 4-(3-hydroxy-...)copy SMILEScopy InChI
Affinity DataIC50: 31.1nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346562(2-cyanoethyl 2,6-dimethyl-7-oxo-4-(4,4,4-trifluoro...)copy SMILES
Affinity DataIC50: 31.2nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346556(US10202378, Example 160 | isobutyl 4-(3-hydroxy-3-...)copy SMILES
Affinity DataIC50: 32.4nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346476(US10202378, Example 89 | US10202378, Example 93a |...)copy SMILES
Affinity DataIC50: 32.9nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346464(US10202378, Example 77 | US10202378, Example 92a |...)copy SMILES
Affinity DataIC50: 33.2nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346492(3-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-4-(3-cyclopr...)copy SMILES
Affinity DataIC50: 33.9nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346511(2-pyridylmethyl 4-(3-hydroxy-3-methyl-but-1-ynyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 34.1nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346592(US10202378, Example 197 | ethyl 4-[3-(3-carbamoylp...)copy SMILES
Affinity DataIC50: 34.1nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346499(Benzyl 4-(3-hydroxy-3-methyl-but-1-ynyl)-2,6-dimet...)copy SMILEScopy InChI
Affinity DataIC50: 34.5nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346501(8-quinolylmethyl 4-(3-cyclopropyl-3-hydroxy-but-1-...)copy SMILES
Affinity DataIC50: 34.6nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346547(1,1-dimethylpropyl 4-(3-hydroxy-3-methyl-but-1-yny...)copy SMILEScopy InChI
Affinity DataIC50: 35.1nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346430(US10202378, Example 43 | ethyl 2,6-dimethyl-7-oxo-...)copy SMILES
Affinity DataIC50: 35.5nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346587(4-(3-cyclopropyl-3-hydroxy-but-1-ynyl)-3-(5-isopro...)copy SMILES
Affinity DataIC50: 36.4nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346532((2-cyano-1,1-dimethyl-ethyl)2,6-dimethyl-7-oxo-4-(...)copy SMILES
Affinity DataIC50: 36.5nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346555(US10202378, Example 159 | cyclohexyl 4-(3-hydroxy-...)copy SMILEScopy InChI
Affinity DataIC50: 36.9nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346502(US10202378, Example 106 | [3-(hydroxymethyl)phenyl...)copy SMILES
Affinity DataIC50: 37.2nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346536(3-acetamidopropyl 4-(3-cyclopropyl-3-hydroxy-but-1...)copy SMILES
Affinity DataIC50: 37.5nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346507(US10202378, Example 111 | [2-(hydroxymethyl)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 37.9nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346447(US10202378, Example 60 | ethyl 4-[2-(3-aminophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 38.1nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346572(4-(3-cyclopropyl-3-hydroxy-but-1-ynyl)-2,6-dimethy...)copy SMILES
Affinity DataIC50: 38.3nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346445(US10202378, Example 58 | ethyl 4-[2-(4-methoxyphen...)copy SMILEScopy InChI
Affinity DataIC50: 38.4nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346450(US10202378, Example 63 | ethyl 4-[2-(3-hydroxyphen...)copy SMILEScopy InChI
Affinity DataIC50: 38.5nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346465(US10202378, Example 78 | ethyl 4-(3-hydroxy-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 38.5nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346543(1,1-dimethylbutyl 4-(3-hydroxy-3-methyl-but-1-ynyl...)copy SMILEScopy InChI
Affinity DataIC50: 38.8nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346401(US10202378, Example 16 | ethyl 4-(3-hydroxy-3-meth...)copy SMILES
Affinity DataIC50: 38.8nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
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